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Renal Cell Carcinoma - Eric A. Klein

Renal Cell Carcinoma

Hardcover Published: 1st January 1993
ISBN: 9780824790332
Number Of Pages: 368

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This reference brings together all aspects of renal cell carcinoma, and provides a basis for understanding the disease's origin, progression and responses to immunotherapy. Examining the current status of cytokine, cell-based and chemotherapeutic methods of treatment, this book: discusses the clinical presentation of advanced renal carcinoma and its therapeutic challenges; reviews prognostic factors and the management of renal cell carcinoma occurring with von Hippel-Landau syndrome; summarizes efforts to identify the tumour suppressor gene deleted from chromosome 3 in most renal cell carcinomas; explicates the role of oncogenes in the progression of renal cell cancer and the molecular correlates of responses to interferon-alpha treatment; details the latest laboratory efforts to establish gene therapy for tumour treatment by transfection of cytokine genes in murine model systems; focuses on biologic response modifier therapy in humans, including cell-mediated immune responses and adoptive immunotherapy; presents preclinical and clinical studies of interleukin-2 alone, in combination with othe cytokines, and with chemothrapeutic agents; and addresses studies on the tumour necrosis factor and low- and high-dose interferon-alpha.

The challenge of advanced renal cell carcinoma
Clinical features
Molecular biology
Cell-mediated immune responses and adoptive immunotherapy
Interleukin-2 and other cytokines
Combination therapy with cytokines
Chemotheray and chemoimmunotherapy
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780824790332
ISBN-10: 0824790332
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 368
Published: 1st January 1993
Publisher: CRC PR INC
Country of Publication: US
Dimensions (cm): 23.57 x 15.95  x 2.31
Weight (kg): 0.68
Edition Number: 1