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Reduction of Sporadic Malignancies by Stimulation of Cellular Repair Systems & by Targeting Cellular Energy Metabolism : Cancer Etiology, Diagnosis and Treatments - Borut Poljsak

Reduction of Sporadic Malignancies by Stimulation of Cellular Repair Systems & by Targeting Cellular Energy Metabolism

Cancer Etiology, Diagnosis and Treatments

Paperback Published: 14th February 2017
ISBN: 9781536107739
Number Of Pages: 70

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About 40% of the population in the industrialised world will develop cancer at some point in their lives, and about half of these people will be cured. Unfortunately, however, approximately one in four Americans alone will die from cancer (over 560,000 Americans each year). Tomasetti and Vogelstein have recently reported that nearly two-thirds of all cancers are caused by random mutations of the body's stem cells. The more random mutations accumulate, the higher the risk of unchecked cell growth, which is a hallmark of cancer development. Knowing the causes of the tumour formation should allow for the development of preventative measures. But what if a tumour is formed due to random mutations during the individuals lifetime? Are there any preventive methods aside from early detection? Reducing the amount of replicative errors must decrease the accumulation rate of random mutations. In this book, the authors provide an overview of approaches that could influence the formation of cancers caused by random mutations, with a focus on methods aimed at modulating genomic stability and/or strengthening the damage repair processes. Targeting cell metabolism through exposure to moderate stress induced by caloric restriction, physical activity or mimetic compounds can activate endogenous defence mechanisms and cellular repair processes.

Preface; Introduction; Mutation Rate Chance and Theories of Mutation; Signaling Pathways Important for Cellular Metabolism, Damage Repair and Defense; Conclusion.

ISBN: 9781536107739
ISBN-10: 1536107735
Series: Cancer Etiology, Diagnosis and Treatments
Format: Paperback
Language: English
Number Of Pages: 70
Published: 14th February 2017
Publisher: Nova Science Publishers Inc
Country of Publication: US
Dimensions (cm): 22.23 x 15.24  x 0.64
Weight (kg): 0.16

Earn 263 Qantas Points
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