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Rang & Dale's Pharmacology : 8th Edition - Humphrey Rang


Published: 21st January 2015
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For 25 years, Rang and Dale's Pharmacology has delivered the core basic and clinical science information required by students and healthcare practitioners worldwide.

Authors H. P. Rang, J. M. Ritter, R. J. Flower, and G. Henderson have ensured that the 8th Edition of this easy-to-read, comprehensive text continues the tradition of excellence with new coverage of drugs affecting the skin and new components online at Student Consult.

Key Features

  • Get the essential pharmacology information you need from one authoritative source with an outstanding global reputation for excellence.
  • Progress confidently through all relevant aspects of pharmacology, beginning with a molecular understanding of receptors and drug actions through clinical uses of key groups of drugs.
  • Find important content quickly thanks to a colour-coded layout that enables easy navigation and cross-referencing.
  • Master difficult concepts with Key Points boxes, Clinical Uses boxes, and full-colour illustrations throughout.
New to this Edition
  • Stay up to date with new information in the field, including an all-new chapter on drugs that affect the skin.
  • Take advantage of new and unique features online, including 500+ chapter-specific multiple choice questions for immediate self-assessment.
  • eBook version included! For the first time, you can access the entire book online or offline across all devices with the Student Consult eBook!
Build your basic and clinical pharmacology knowledge with a comprehensive yet easy-to-use text



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    "This textbook nimbly covers a wide, complex subject without dumbing it down...It's easy to read (in bite sized chunks) and the liberal use of colour, and high quality paper, add a feel-good factor." BMA Awards 2007, review of the previous edition

    Section 1: General principles
    1. What is pharmacology?
    2. How drugs act: general principles
    3. How drugs act: molecular aspects
    4. How drugs act: cellular aspects-excitation, contraction and secretion
    5. Cell proliferation, apoptosis, repair and regeneration
    6. Cellular mechanisms: host defence
    7. Method and measurement in pharmacology
    8. Drug absorption and distribution
    9. Drug metabolism and elimination
    10. Pharmacokinetics
    11. Pharmacogenetics, pharmacogenomics and 'personalised medicine'
    Section 2: Chemical mediators
    12. Chemical mediators and the autonomic nervous system
    13. Cholinergic transmission
    14. Noradrenergic transmission
    15. 5-Hydroxytryptamine and the pharmacology of migraine
    16. Purines
    17. Local hormones: cytokines, biologically active lipids, amines and peptides
    18. Cannabinoids
    19. Peptides and proteins as mediators
    20. Nitric oxide
    Section 3: Drugs affecting major organ systems
    21. The heart
    22. The vascular system
    23. Atherosclerosis and lipoprotein metabolism
    24. Haemostasis and thrombosis
    25. Haemopoietic system and treatment of anaemia
    26. Anti-inflammatory and immunosuppressant drugs
    27. The respiratory system
    28. The kidney
    29. The gastrointestinal tract
    30. The control of blood glucose and drug treatment of diabetes mellitus
    31. Obesity
    32. The pituitary and the adrenal cortex
    33. The thyroid
    34. The reproductive system
    35. Bone metabolism
    Section 4: The nervous system
    36. Chemical transmission and drug action in the central nervous system
    37. Amino acid transmitters
    38. Other transmitters and modulators
    39. Neurodegenerative diseases
    40. General anaesthetic agents
    41. Analgesic drugs
    42. Local anaesthetics and other drugs affecting sodium channels
    43. Anxiolytic and hypnotic drugs
    44. Antiepileptic drugs
    45. Antipsychotic drugs
    46. Antidepressant drugs
    47. CNS stimulants and psychotomimetic drugs
    48. Drug addiction, dependence and abuse
    Section 5: Drugs used for the treatment of infections, cancer and immunological disorders
    49. Basic principles of antimicrobial chemotherapy
    50. Antibacterial drugs
    51. Antiviral drugs
    52. Antifungal drugs
    53. Antiprotozoal drugs
    54. Anthelminthic drugs
    55. Anticancer drugs
    Section 6: Special topics
    56. Individual variation and drug interaction
    57. Harmful effects of drugs
    58. Lifestyle drugs and drugs in sport
    59. Biopharmaceuticals and gene therapy
    60. Drug discovery and development

    ISBN: 9780702053627
    ISBN-10: 0702053627
    Audience: Tertiary; University or College
    Format: Paperback
    Language: English
    Number Of Pages: 776
    Published: 21st January 2015
    Publisher: Elsevier Health Sciences
    Country of Publication: GB
    Dimensions (cm): 27.9 x 21.5  x 2.9
    Weight (kg): 1.86
    Edition Number: 8
    Edition Type: Revised