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Radical-Mediated Protein Oxidation : From Chemistry to Medicine - Michael J. Davies

Radical-Mediated Protein Oxidation

From Chemistry to Medicine

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Radicals--short lived, reactive molecules--are thought to play a major role in many oxidative processes within cells and to have implications in several human diseases, carcinogenesis, and aging. This unique and comprehensive volume brings together up-to-date information on the oxidation of amino acids, peptides, and proteins by free radicals and discusses the roles of such processes in biological systems. Topics include: the chemistry of amino acid and protein oxidation; the biochemical consequences of these reactions; the role of protein oxidation in normal physiology; the potential importance of protein oxidation in human health, including aging, heart disease, cancer, inflammation, and neurodegenerative diseases; and the possible prevention of disease processes by antioxidants and other protective strategies. Drawing on the latest research across a range of disciplines, this book will be important reading for researchers and graduate and postdoctoral students in the fields of radical biochemistry, physiology, and pathology.

`This comprehensive text includes a great deal of relevant information on this important topic and discusses protein oxidation in many biological systems.' Aslib Book Guide, vol.63, no.2, Feb.98 `This is an excellent and long-overdue book...this excellent book should be widely read by everyone in the free radical field. I recommend it highly.' Halliwell, Free Rad.Res,Vol.29

A historical survey of the study of radical-mediated protein oxidation Formation and chemistry of radicals involved in amino acid, peptide, and protein oxidation The biochemistry of protein oxidation in cells and cell-free systems The physiology of protein oxidation Pathology of protein oxidation Future directions in the study of protein oxidation References Index

ISBN: 9780198500971
ISBN-10: 0198500971
Series: Oxford Science Publications
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 456
Published: 1st January 1998
Country of Publication: GB
Dimensions (cm): 24.13 x 16.51  x 3.18
Weight (kg): 0.79