Radicals--short lived, reactive molecules--are thought to play a major role in many oxidative processes within cells and to have implications in several human diseases, carcinogenesis, and aging. This unique and comprehensive volume brings together up-to-date information on the oxidation of amino acids, peptides, and proteins by free radicals and discusses the roles of such processes in biological systems. Topics include: the chemistry of amino acid and protein oxidation; the biochemical consequences of these reactions; the role of protein oxidation in normal physiology; the potential importance of protein oxidation in human health, including aging, heart disease, cancer, inflammation, and neurodegenerative diseases; and the possible prevention of disease processes by antioxidants and other protective strategies. Drawing on the latest research across a range of disciplines, this book will be important reading for researchers and graduate and postdoctoral students in the fields of radical biochemistry, physiology, and pathology.
`This comprehensive text includes a great deal of relevant information on this important topic and discusses protein oxidation in many biological systems.'
Aslib Book Guide, vol.63, no.2, Feb.98
`This is an excellent and long-overdue book...this excellent book should be widely read by everyone in the free radical field. I recommend it highly.'
Halliwell, Free Rad.Res,Vol.29
A historical survey of the study of radical-mediated protein oxidation
Formation and chemistry of radicals involved in amino acid, peptide, and protein oxidation
The biochemistry of protein oxidation in cells and cell-free systems
The physiology of protein oxidation
Pathology of protein oxidation
Future directions in the study of protein oxidation
Series: Oxford Science Publications
Number Of Pages: 456
Published: 1st January 1998
Country of Publication: GB
Dimensions (cm): 23.62 x 15.95
Weight (kg): 0.8