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Psychiatry, Psychoimmunology and Viruses : Key Topics in Brain Research, - Norbert Muller

Psychiatry, Psychoimmunology and Viruses

Key Topics in Brain Research,

By: Norbert Muller (Editor)

Paperback Published: July 1999
ISBN: 9783211832493
Number Of Pages: 156

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The contributions in this book deal with basic research in psychoneuroimmunology, dysfunctions of the immune system in psychiatric disorders and the possible role of viruses in psychoneuroimmunological processes. Growing knowledge about the reciprocal relationship between psychic processes and the immune system is interest to clinical psychiatrists in this field because immunological dysfunction is found in depression and schizophrenia, but also in other psychiatric syndromes like anxiety disorders. The chapter authors, all active researchers in the field, describe the results of their scientific work. The interdisciplinary character of this book is outlined by the broad international and disciplinary range of the authors which represent a spectrum from basic scientists such as pharmacologists and immunologists, to clinical psychiatrists and neurologists. Findings regarding the role of the immune system in sleep and in headache are discussed. Special emphasis is placed on methodological pitfalls in immunological studies of psychiatric disorders. Perspectives for future therapeutical strategies are outlined.

Viruses and the immune system in psychiatric disorders
Immunogenetic aspects of viral or other environmental factors in schizophreniap. 1
The use of subtraction libraries for the identification of RNA species upregulated in the brains of individuals with schizophreniap. 7
Cerebrospinal fluid filtration in a case of schizophrenia related to "subclinical" Borna disease virus encephalitisp. 19
Borna disease virus in patients with psychiatric disorders or fibromyalgia - demonstration of antibodies is highly dependent on the detection methodp. 37
Serotonergic system, depression, and immune system
Interaction of the serotonergic and the immune systems: 5HT-Modulinep. 45
The inflammatory response system activation model of major depressionp. 55
Schizophrenia and the immune system
Methodological concerns in the study of the immune system in schizophreniap. 63
Psychoimmunological alterations in schizophrenia: how do confounding variables influence the findings?p. 71
On the myth of antibrain antibodies in schizophrenia - a critical overviewp. 81
Schizophrenia: the teratogenic antibody hypothesisp. 89
A preliminary analysis investigating immune activation in schizophreniap. 101
Measurement of neopterin, kynurenine and tryptophan in sera of schizophrenic patientsp. 115
Levels of soluble adhesion molecules in schizophrenia: relation to psychopathologyp. 121
Sleep, anxiety, headache, and immunity
The role of interferon-alpha in the regulation of sleepp. 131
Immunological alterations in patients suffering from bulimia nervosa (DSM-IV 307.51) vs anxiety disorders (DSM-IV 300.01, 300.21, 309.81, 300.02)p. 145
T cell subsets and expression of integrins in peripheral blood of patients with migraine and chronic tension type headachep. 153
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9783211832493
ISBN-10: 3211832491
Series: Key Topics in Brain Research,
Audience: General
Format: Paperback
Language: English
Number Of Pages: 156
Published: July 1999
Country of Publication: AT
Dimensions (cm): 22.86 x 15.24  x 0.94
Weight (kg): 0.24