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Protein Phosphatases : Topics in Current Genetics, 5 - Joaquin Arino

Protein Phosphatases

Topics in Current Genetics, 5

By: Joaquin Arino (Editor), Denis Alexander (Editor)

Hardcover

Published: January 2004
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Overview of Protein Serine/Threonine Phosphatases.- Protein Phosphatase 1.- Protein Phosphatase 2A: A Multifunctional Regulator of Cell Signaling.- Calcineurin: Roles of the Ca2+/Calmodulin-dependent Protein Phosphatase in Diverse Eukaryotes.- Roles of Mammalian Protein Phosphatase 2C Family Members in the Regulation of Cellular Functions.- PP5: the TPR Phosphatase.- Protein Histidine Phosphatases in Signal Transduction and Metabolism.- Anchoring of Protein Kinase and Phosphatase Signaling Units.- Functional Proteomics in Phosphatase Research.- Structure and Function of the T-cell Protein Tyrosine Phosphatase.- Protein Tyrosine Phosphatase-based Therapeutics: Lessons From PTP1B.- The CD45 Phosphotyrosine Phosphatase.- Receptor Protein Tyrosine Phosphatases.- The Shp-2 Tyrosine Phosphatase.- SHP-1 Twelve Years on: Structure, Ligands, Substrates and Biological Roles.- The Dual-specific Protein Tyrosine Phosphatase Family.- Tyrosine Phosphatases in Cancer: Targets for Therapeutic Intervention.

Overview of protein serine/threonine phosphatasesp. 1
Protein phosphatase 1p. 21
Protein phosphatase 2A: A multifunctional regulator of cell signalingp. 45
Calcineurin: Roles of the Ca[superscript 2+]/calmodulin-dependent protein phosphatase in diverse eukaryotesp. 73
Roles of mammalian protein phosphatase 2C family members in the regulation of cellular functionsp. 91
PP5: the TPR phosphatasep. 107
Protein histidine phosphatases in signal transduction and metabolismp. 131
Anchoring of protein kinase and phosphatase signaling unitsp. 145
Functional proteomics in phosphatase researchp. 167
Structure and function of the T-cell protein tyrosine phosphatasep. 185
Protein tyrosine phosphatase-based therapeutics: lessons from PTPIBp. 201
The CD45 phosphotyrosine phosphatasep. 231
Receptor protein tyrosine phosphatasesp. 253
The Shp-2 tyrosine phosphatasep. 275
SHP-1 twelve years on: structure, ligands, substrates and biological rolesp. 301
The dual-specific protein tyrosine phosphatase familyp. 333
Tyrosine phosphatases in cancer: Targets for therapeutic interventionp. 359
Indexp. 375
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9783540205609
ISBN-10: 3540205608
Series: Topics in Current Genetics, 5
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 378
Published: January 2004
Publisher: Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
Country of Publication: DE
Dimensions (cm): 23.5 x 15.88  x 2.54
Weight (kg): 0.86