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Protein Folding : In Vivo and in Vitro - Jeffrey L. Cleland

Protein Folding

In Vivo and in Vitro

By: Jeffrey L. Cleland (Editor)

Hardcover Published: 5th May 1993
ISBN: 9780841226401
Number Of Pages: 258

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Covers the most recent advances in the field of protein folding and its impact on future technologies. Reviews in vivo aspects such as mechanisms of inclusion body formation and molecular chaperones, and includes highlights of Jonathan King's work at MIT. In vitro aspects examined include methods of protein folding, recovery of commercial protein products, and genetic approaches to understanding and solving protein folding problems. Written by leading scientists in the field, the volume provides a linkage between fundamental academic research and industrial applications of protein folding technology.

Impact of Protein Folding on Biotechnology
Amino AcidSequence Determinants of Polypeptide Chain Folding and Inclusion Body Formation
Duplicated Segment of Clostridium thermocellum Cellulases
Probing the Role of Protein Folding inInclusion Body Formation
Experimental Investigation of the In Vivo Kinetics ofInclusion Body Formation
MolecularChaperones and Their Role in Protein Assembly
Role of Molecular Chaperones in Transport ofProteins into the Mammalian Endoplasmic Reticulum: Solubilization-AchievingProteins, Folding-Accelerating Proteins, and Translocation-Mediating Proteins
Folding of Recombinant Human Insulin-Like GrowthFactor-1 in Yeast
Role of the Protein-Folding Chaperone BiP inSecretion of Foreign Proteins in Eukaryotic Cells
GroEL-Mediated Protein Folding
Prolyl Isomerizations asRate-Determining Steps in the Folding of Ribonuclease T1P.M. Horowitz: Kinetic Control of Protein Folding by Detergent Micelles,Liposomes, and Chaperonins
Comparison of Amino Acid Helix Propensities(s-values) in Different Experimental Systems
Single-Step Solubilization and Folding of IGF-1Aggregates from Escherichia coli
Role ofDisulfide Bonds in Folding of Recombinant Human Granulocyte Colony StimulatingFactor Produced in Escherichia coli
In Vivo Expression of Correctly Folded AntibodyFragments from Microorganisms
Characterization of Humanized Anti-p185HER2 Antibody Fab Fragments Produced inEscherichia coli
Spectral Analysis of Site-Directed Mutantsof Human Growth Hormone
Altering the Self-Association and Stability of Insulin by AminoAcid Replacement
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780841226401
ISBN-10: 0841226407
Series: ACS Symposium Series
Audience: General
Format: Hardcover
Language: English
Number Of Pages: 258
Published: 5th May 1993
Publisher: AMER CHEMICAL SOC
Country of Publication: US
Dimensions (cm): 24.74 x 15.9  x 2.16
Weight (kg): 0.62

Earn 319 Qantas Points
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