Volume 37 of "Progress in Drug Research" contains seven articles and the various indexes which facilitate its use and establish the connection with the previous volumes. While all articles deal with some of the topical aspects of drug research, the contribution by Al- fred Burger on "Isosterism and bioisosterism in drug design" is of great value to those researchers who are engaged in drug design and wish to include isosteric considerations in establishing a work- ing hypothesis. The remaining six reviews provide an overview of the work in- volved in the search for new and better medicines. All these articles contain surveys of the latest findings in the respective domain. In the 31 years this series has existed, the Editor has enjoyed the help and advise of many colleagues. Readers, the authors of the in- dividual reviews and, last but 'not least, the reviewers have all con- tributed greatly to the success of PDR. Although many comments received have been favorable, it is nevertheless also necessary to an- alyze and to reconsider the current position and the direction of such a series.
* Inhalt * Sommaire.- Leukotriene antagonists and inhibitors of leukotriene biosynthesis as potential therapeutic agents.- Bacterial resistance to antibiotics: The role of biofilms.- Pharmacological properties of the natural polyamines and their depletion by biosynthesis inhibitors as a therapeutic approach.- Potassium channel openers: Airway pharmacology and clinical possibilities in asthma.- Antifungal chemotherapy: Are we winning?.- The hopanoids, bacterial triterpenoids, and the biosynthesis of isoprenic units in prokaryotes.- Isosterism and bioisosterism in drug design.- Index * Sachverzeichnis * Table des matieres, Vol. 37.- Index of titles * Verzeichnis der Titel * Index des titres * Vol. 1-37.- Author and paper index * Autoren- und Artikelindex * Index des auteurs et des articles, Vol. 1-37.
Series: Progress in Drug Research
Number Of Pages: 419
Published: December 1991
Publisher: SPRINGER VERLAG GMBH
Country of Publication: CH
Dimensions (cm): 24.41 x 16.99
Weight (kg): 0.67