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Population Genetics : A Concise Guide - John H. Gillespie

Population Genetics

A Concise Guide

Paperback Published: 7th September 2004
ISBN: 9780801880094
Number Of Pages: 232
For Ages: 22+ years old

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This concise introduction offers students and researchers an overview of the discipline that connects genetics and evolution. Addressing the theories behind population genetics and relevant empirical evidence, John Gillespie discusses genetic drift, natural selection, nonrandom mating, quantitative genetics, and the evolutionary advantage of sex. First published to wide acclaim in 1998, this brilliant primer has been updated to include new sections on molecular evolution, genetic drift, genetic load, the stationary distribution, and two-locus dynamics. This book is indispensable for students working in a laboratory setting or studying free-ranging populations.

"John Gillespie has done the near-impossible, condensing the essence of population genetics into a very short book. The result is a little gem. The derivations are simple and clear, and often strikingly original. The minor gaps in the first edition are filled by this equally concise second edition. Population genetics is a complicated subject; only a person of Gillespie's depth of knowledge and insight could simplify without distorting." - James F. Crow, author of Genetics Notes "The book is coherently and logically structured and covers all the most important and incontrovertible aspects of population genetics... I recommend this as a good introductory book that can be used in both undergraduate and graduate courses." - Heredity "A well-developed, thoughtful, and classic book that has been tested and improved through many years in the classroom... A 'must' for anyone interested in plant or animal genetics." - Choice"

List of Figuresp. ix
Prefacep. xi
Genetic Variationp. 1
DNA variation in Drosophilap. 2
Loci and allelesp. 6
Genotype and allele frequenciesp. 10
The Hardy-Weinberg lawp. 12
Answers to problemsp. 18
Genetic Driftp. 21
A first look at genetic driftp. 22
The decay of heterozygosityp. 25
Mutation and driftp. 29
Molecular evolutionp. 32
The neutral theoryp. 36
The coalescentp. 40
The effective size of a populationp. 47
Another model of genetic driftp. 49
The stationary distributionp. 53
Is genetic drift important in evolution?p. 55
Answers to problemsp. 56
Natural Selectionp. 59
The fundamental modelp. 61
Relative fitnessp. 62
Three kinds of selectionp. 64
Mutation-selection balancep. 70
Genetic loadp. 71
The heterozygous effects of allelesp. 76
Changing environmentsp. 85
The stationary distributionp. 90
Selection and driftp. 91
Molecular evolutionp. 95
Answers to problemsp. 98
Two-Locus Dynamicsp. 101
Linkage disequilibriump. 101
Two-locus selectionp. 105
Genetic draftp. 111
Answers to problemsp. 116
Nonrandom Matingp. 119
Generalized Hardy-Weinbergp. 120
Identity by descentp. 121
Inbreedingp. 123
The evolution of selfingp. 127
Subdivisionp. 131
Answers to problemsp. 136
Quantitative Geneticsp. 139
Correlation between relativesp. 139
Response to selectionp. 150
Evolutionary quantitative geneticsp. 154
Dominancep. 160
The intensity of selectionp. 166
Answers to problemsp. 168
The Evolutionary Advantage of Sexp. 169
Genetic segregationp. 170
Crossing-overp. 173
Muller's ratchetp. 174
Kondrashov's hatchetp. 179
Answers to problemsp. 183
Mathematical Necessitiesp. 185
Probabilityp. 189
Bibliographyp. 207
Indexp. 211
Table of Contents provided by Ingram. All Rights Reserved.

ISBN: 9780801880094
ISBN-10: 0801880092
Audience: Tertiary; University or College
For Ages: 22+ years old
Format: Paperback
Language: English
Number Of Pages: 232
Published: 7th September 2004
Publisher: Johns Hopkins University Press
Country of Publication: US
Dimensions (cm): 22.9 x 15.6  x 1.5
Weight (kg): 0.33
Edition Number: 2
Edition Type: Revised