These volumes cover all relevant aspects of recent research in estrogens and antiestrogens from chemistry, physiology, pharmacology to clinical applications. Particular emphasis is devoted to new developments in the area of estrogen receptors including estrogen receptor a and the mode of action of novel partial estrogen agonists/ antagonists. Further topics address the importance of estrogen and antiestrogens in fertility, aging, cancer, animal husbandry and the environment. Part I discusses the complex chemistry of steroidal and non-steroidal estrogens and antiestrogens as well as the molecular mechanisms of estrogen action. The volume provides information on the metabolism and the various physiological and pathophysiological responses of estrogens. The chapters have been written by experts in the field of endocrinology for researchers, lecturers, physicians and pharmacologists. Due to their broad scope these volumes will be indispensable reference books in any library.
Part I: Chemistry of Estrogens and Antiestrogens; Molecular Biology of Estrogenic Action; Biosynthesis and Metabolism of Endogenous Estrogens; Physiology and Pathophysiology of Estrogens.- Part II: Pharmacology of Estrogens and Antiestrogens; Toxicology of Estrogens and Antiestrogens; Clinical Application and Potential of Estrogens and Antiestrogens; Comparative Endocrinology; Estrogens, Antiestrogens and Environment.
Series: Handbook of Experimental Pharmacology : Book 1
Number Of Pages: 409
Publisher: Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
Country of Publication: DE
Dimensions (cm): 23.39 x 15.6
Weight (kg): 0.79