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Pharmacotherapy of Obesity : Options and Alternatives - Karl G. Hofbauer

Pharmacotherapy of Obesity

Options and Alternatives

Hardcover Published: 14th June 2004
ISBN: 9780415303217
Number Of Pages: 504

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Drug treatment of obesity remains a controversial topic. Opinions range from advocating life-long treatment of obesity with a single drug or drug combination, to opposing drug treatment of obesity because of its inevitable use as "lifestyle drugs." Clarifying the debate, Pharmacotherapy of Obesity: Options and Alternatives explores current and future options for drug treatment for obesity in the context of pathophysiology and clinical requirements and then puts them into perspective against available alternative treatments. Distinguished scientists and clinical investigators provide state-of-the-art reviews of each individual topic, which covers a wide range of subjects from pathophysiology of obesity to the benefits of weight loss. The core sections on pharmacotherapy deal with currently available drugs and drugs in pre-clinical development, complemented with sections on non-drug treatment and general therapeutic aspects. This design provides an integrated view of therapeutic approaches to the treatment of obesity and its associated syndromes.

Pathophysiology of Obesity
Energy Homeostasisp. 3
The Pathophysiology of Appetite Controlp. 25
Genetics of Obesityp. 53
Antipsychotic Drugs, Weight Gain, and Diabetesp. 69
General Therapeutic Aspects
Obesity and Associated Complicationsp. 87
Psychosocial Aspects of Obesityp. 119
Basic Considerations and Guidelines for Treatmentp. 139
Benefits of Weight Loss
Weight Loss and Cardiovascular Risk Factorsp. 155
Weight Loss and Associated Diseasesp. 173
Weight Loss and Metabolic Diseasesp. 195
Drugs on the Market
Orlistatp. 219
Sibutraminep. 245
Noradrenergic, Serotonergic, Antiepileptic, and Herbal Drugsp. 267
Adverse Effects and Drug-Drug Interactionsp. 285
Drugs in Research and Development
Central Targets for Antiobesity Drugsp. 299
Leptin and Other Appetite Suppressantsp. 321
Peripheral Targets for Antiobesity Drugsp. 345
Targeting Thermogenesis in the Development of Antiobesity Drugsp. 363
Treatment Alternatives
Diet, Physical Activity, and Behaviorp. 387
Dietary Supplements and Herbal Preparationsp. 405
Surgical Treatment of Obesityp. 421
Efficacy of Different Antiobesity Interventionsp. 435
Integrated Approach to Treatment and Preventionp. 449
Perspectives and Outlookp. 467
Indexp. 473
Table of Contents provided by Rittenhouse. All Rights Reserved.

ISBN: 9780415303217
ISBN-10: 0415303214
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 504
Published: 14th June 2004
Publisher: Taylor & Francis Ltd
Country of Publication: GB
Dimensions (cm): 25.4 x 17.8  x 3.18
Weight (kg): 1.02
Edition Number: 1