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Pharmacotherapies for the Treatment of Opioid Dependence : Efficacy, Cost-Effectiveness and Implementation Guidelines - Richard P. Mattick

Pharmacotherapies for the Treatment of Opioid Dependence

Efficacy, Cost-Effectiveness and Implementation Guidelines

By: Richard P. Mattick (Editor), Robert Ali (Editor), Nicholas Lintzeris (Editor)

Paperback

Published: 22nd February 2013
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The most comprehensive text of its kind, this book addresses both the management of opioid withdrawal and opioid maintenance therapy, and combines up-to-date reviews of the scientific literature with evidence-based clinical guidelines for all of the relevant pharmacotherapies.

A unique work, Pharmacotherapies for the Treatment of Opioid Dependence presents:

·        detailed information on the cost-effectiveness of the various types of opioid treatment

·        the range of pharmacotherapies used for the management of opioid dependence

·        the state of knowledge from the international research literature on the value and relative efficacy of the various pharmacological approaches.

This includes pharmacotherapies used in the management of withdrawal from opioids such as clonidine, lofexidine, methadone, buprenorphine and naltrexone and also symptomatic medications. It also includes different forms of maintenance therapy using opioid agonists such as methadone, LAAM, buprenorphine, slow-release oral morphine and diamorphine, and opioid antagonists such as naltrexone.

This text should appeal to researchers, to identify gaps in the research literature and provide a basis for determining appropriate research directions, to clinicians by providing clinical with clinical guidelines and information concerning the empirical basis for the treatments, and to policy makers in assisting them to make decisions about the various treatments from a public health perspective, taking into account the relative cost and effectiveness of the interventions.

List of contributorsp. viii
Forewordp. xi
Acknowledgmentsp. xiv
Introduction
Opioid Dependence and Managementp. 1
Pharmacology of opioid agonists and antagonistsp. 15
Outcomes for Withdrawal
Services for heroin withdrawal: A reviewp. 54
Outcomes for Maintenance Treatment
Methadone maintenance treatmentp. 107
LAAM in the treatment of opioid dependence: A systematic reviewp. 142
The place of buprenorphine in the management of opioid dependencep. 193
Treating heroin dependence with diamorphine (pharmaceutical heroin)p. 227
Naltrexone maintenance treatmentp. 252
Outcomes from the National Evaluation of Pharmacotherapies for Opioid Dependence (NEPOD) Project
Pharmacotherapies and pregnancyp. 282
Politics, practice, and research into treatment of heroin addictionp. 330
Clinical guidelines and procedures for the use of methadone in the maintenance treatment of opioid dependencep. 354
National clinical guidelines and procedures for the use of buprenorphine in the treatment of heroin dependencep. 390
Clinical guidelines and procedures for the use of naltrexone in the management of opioid dependencep. 446
Choosing treatments: The role of economics in informing future decisionsp. 475
Indexp. 489
Table of Contents provided by Ingram. All Rights Reserved.

ISBN: 9781841844008
ISBN-10: 1841844004
Audience: Professional
Format: Paperback
Language: English
Number Of Pages: 506
Published: 22nd February 2013
Publisher: Taylor & Francis Ltd
Country of Publication: GB
Dimensions (cm): 22.86 x 15.24  x 2.54
Weight (kg): 0.82
Edition Number: 1