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Pathophysiology of Pain Perception : Springer Series in Rehabilitation and Health - Stefan Lautenbacher

Pathophysiology of Pain Perception

Springer Series in Rehabilitation and Health

By: Stefan Lautenbacher (Editor), Roger B. Fillingim (Editor)

Hardcover Published: 30th April 2004
ISBN: 9780306481154
Number Of Pages: 232

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Readers have access to legions of books dealing with the molecular, genetic, neurochemical, neurophysiological, neuroanatomical, neuroradiological and psychological aspects of pain as well as with the clinical approaches to pain from various medical disciplines. Why then is it necessary to publish a book on the pathophysiologyofpain perception? Pain can result either from noxious events due to lesions, injuries, diseases, etc. , or from disturbances in the system transducing, transforming, and processing the potential pain signal or from an interaction of both. Under certain pathological conditions, the pain-processing system, which includes both physiological and psychological components, can produce the experience of pain in the absence of any peripheral noxious event. This book primarily ex­ amines these pathological alterations in the pain-signalling system, and the authors provide information on the functioning of the pain-processing system under normal and pathological conditions. The understanding of pain perception is essential for optimal diagnosis and treatment of acute and chronic pain. Considerable evidence now indicates that alterations in pain per­ ception are characteristic of many clinical pain states. Whether disturbed pain perception is a truly etiological or only a maintaining factor-c-or even a mere epiphenomenon of chronic functional pain-is reviewed in detail by L. Arendt-Nielsen, C. R. Covelli, R. B. Fillingim,]. M. Gillespie, T. Graven-Nielsen, E. Kosek, S. Lautenbacher, M. Peters, A. Pielsticker, DO. Price, G. B. Rollman, P. Svensson and G. N. Verne for headache, back pain, fibromyalgia, myofascial pain, temporomandibular pain disorder, irritable bowel syndrome and menstrual cycle-related pain disorders.

Basic Physiology of Pain Perception
Introduction to Nociception, Acute and Chronic Pain
Animal Studies on Nociception and Pain
The Peripheral Nociceptive System
The Central Pain System
The Physiology of Nociceptive Processing in the CNS
Assessment of Pain Perception
Experimental Methods for Pain Induction
Experimental Methods of Pain Assessment
Disturbances of Pain Perception in Primary Headache: Migraine, Tension-Type and Cluster Headaches
Description of the Syndromes
Pain and Functional Impairment
Psychological Antecedents, Cause and Sequels
Muscle Tension and Vascular Reactions
Central Factors
Disturbance of Pain Perception
Cephalic Pain Sensitivity
Extra-Cephalic Pain Sensitivity
Disturbances of Pain Perception in Chronic Back Pain
Description of the Disorder
Disturbances in Pain Perception
Disturbances of Pain Perception in Fibromyalgia
Description of the Syndrome
Concluding Remarks
Disturbances of Pain Perception in Myofascial Pain Syndrome and Other Musculoskeletal Pains
Definition of MPS. General Characteristics of MPS. Trigger Points in MPS. Referred Pain in Musculoskeletal Pain Conditions
Hyperalgesia in Musculoskeletal Pain Conditions
Disturbances in Pain Perception in Temporomandibular Pain Syndrome
Contrasting Concepts
Regional or Widespread Disorder
Response to Non-Noxious Stimuli
Experimental Models of TMD. Studies of Neurotransmitters
Respone to Stress
Disturbances of Pain Perception in Irritable Bowel Syndrome
Definition and Clinical Presentation
IBS as a Neurologic Disorder
Animal Models of Persistent Pain State Mechanism
Human Neural Imaging Studies of Persistent Pain Conditions
Somatic Pain Testing in IBS Patients
Serotonin and IBS. Psychological Factors in IBS. Conclusions
Pain Perception Across the Menstrual Cycle
Premenstrual Syndrome
Menstrual Cycle Influences on Other Chronic Pain Disorders
Disturbances of Pain Perception in Disorders of the Peripheral Nervous System
Diabetic Polyneuropathy
Complex Regional Pain Syndrome (CRPS)
Herpes Zoster
Trigeminal Neuralgia
Lumbosacral Radiculopathy
Disturbances of Pain Perception in Disorders of the Peripheral and Central Nervous System
General Considerations
The Clinical Diagnosis of Neuropathic Pain
Syndromes which may be Accompanied by Neuropathic Pain
Pain Perception in Psychiatric Disorders
Anorexia Nervosa and Bulimia Nervosa
Borderline Personality Disorder
Alterations in Pain Perception in Cardiovascular Disease
Cardiovascular Variables and Pain Perception
Mechanisms of Blood Pressure-Related Hypoalgesia
Pain Perception in Coronary Artery Disease and Other Cardiac Diseases
Perception of Pain during Pregnancy and Labor
Physiological Changes During Pregnancy
Pain and Discomfort in Pregnancy
Physiology of Labor
Labor Pain
Memory for Labor Pain
Factors Affecting Pain during Labor
The Effect of Acupuncture on Pain and Use of Analgesics during Labor
The Role of Endogenous Opioids in Pain Processing during Pregnancy and Labor
Experimental Studies of Pain Perception in Pregnancy and Labor
The Importance of Quantitative Sens
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780306481154
ISBN-10: 0306481154
Series: Springer Series in Rehabilitation and Health
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 232
Published: 30th April 2004
Publisher: Springer Science+Business Media
Country of Publication: US
Dimensions (cm): 23.5 x 15.5  x 1.91
Weight (kg): 1.17