Pancreatic Islet Cell Regeneration and Growth

By: Aaron I. Vinik (Editor)

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200 Pages

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The proceedings of a Diabetes Institute conference in Norfolk, Virginia, June 1991. The 19 papers cover the regulation of cell growth and development, models for the study of cell regeneration, the induction of cell growth and mechanisms, and pathogenic and therapeutic ramifications. The contributor

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Non-Fiction Medicine Clinical & Internal Medicine Endocrinology Pre-Clinical Medicine & Basic Sciences Physiology Metabolism Medicine in General Health Systems & Services General Practice Science Biology, Life Sciences

Life Sciences in General Genetics excluding Medical Biochemistry Zoology & Animal Sciences

Introduction	p. 1
Regulation of Cell Growth and Development
The Role of Growth Hormone and Prolactin in Beta-Cell Growth and Regeneration	p. 9
The Insulin-Like Growth Factor Family of Peptides, Binding Proteins and Receptors: Their Potential Role in Tissue Regeneration	p. 21
The Effects of IGF-I and IGF-II on Cell Growth and Differentiation in the Central Nervous System	p. 31
Growth Factor Expression in Normal and Diabetic Rats During Peripheral Nerve Regeneration through Silicone Tubes	p. 37
Oncogenes and Cell Growth	p. 45
Interferon - A Candidate Mediator of Cell Growth	p. 53
Models for the Study of Cell Regeneration
Islet Beta-Cell Regeneration and Reg Genes	p. 61
Factors Regulating Islet Regeneration in the Post-Insulinoma NEDH Rat	p. 71
Regeneration of Pancreatic Endocrine Cells in Interferon Gamma Transgenic Mice	p. 85
Trophic Stimulation of the Ductular-Islet Cell Axis: A New Approach to the Treatment of Diabetes	p. 95
Induction of Cell Growth and Mechanisms
Expression of Insulin-Like Growth Factors (IGFs) and Their Binding Proteins (IGF BPs) During Pancreatic Development in Rat, and Modulation of IGF Actions on Rat Islet DNA Synthesis by IGF BPs	p. 113
The Partial Isolation and Characterization of Ilotropin, A Novel Islet-Specific Growth Factor	p. 123
Expression of Growth Factort in a Pancreatic Islet Regeneration Model	p. 133
Role of p21[superscript ras] in Hormone Signalling and Cell Growth Transformation	p. 143
Phosphoinositides and Cell Growth	p. 147
The Physiological STOP Pathway: Target Regulation of Axonal Growth	p. 153
Cell Calcium Regulation of Myosin I - A Motor for Membrane Movement	p. 159
Pathogenic and Therapeutic Ramifications
Amylin Expression in the Pancreatic Beta-Cell	p. 167
Studies of Composite Grafts of Fetal Pancreas (FP) and Fetal Liver (FL) in the Streptozotocin-Induced Diabetic Rat	p. 171
Contributors	p. 179
Index	p. 183
Table of Contents provided by Blackwell. All Rights Reserved.

Pancreatic Islet Cell Regeneration and Growth

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Hardcover

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