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Pancreatic Disease : State of the Art and Future Aspects of Research - Paul G. Lankisch

Pancreatic Disease : State of the Art and Future Aspects of Research

By: Paul G. Lankisch (Editor), Eugene P. DiMagno (Editor)

Paperback ISBN: 9783540653578
Number Of Pages: 272

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This symposium volume summarizes research that has advanced our understanding of both the basic mechanisms of pancreatic physiology and pathophysiology and the diagnosis and treatment of the diseases of the exocrine pancreas. By doing so, it serves to give direction to future research. Diseases discussed include acute and chronic pancreatitis, cystic fibrosis, and pancreatic cancer. The volume also reflects a central concern of the symposium: to stimulate young persons embarking on a career in this area.

Acute Pancreatitis
Acute Pancreatitis: Mechanisms of Cell Injury - Geneticsp. 3
Events Inside the Pancreatic Acinar Cell in Acute Pancreatitis: Role of Secretory Blockade, Calcium Release and Dehydration for the Initiation of Trypsinogen Activation and Autodigestionp. 14
Immunologic Mechanisms in Acute Pancreatitisp. 24
Mechanisms in Cellular Injuryp. 36
Acute Pancreatitis: Bacterial Translocation and Pancreatic Infectionsp. 39
Staging and Early Nasolateral Feeding in Acute Pancreatitisp. 55
Acute Pancreatitis: Medical and Endoscopic Treatmentp. 66
Surgical Treatment of Acute Pancreatitisp. 78
Chronic Pancreatitis
Chronic Pancreatitis: Do Different Etiologies (Alcohol, Obstruction) Invoke Different Mechanisms?p. 93
Exocrine Pancreatic Secretion, Pain, and Malabsorptionp. 102
Intestinal Transit of Chyme and its Regulatory Role: Clinical Implicationsp. 112
Treatment of Exocrine Pancreatic Insufficiency in Chronic Pancreatitisp. 121
Mechanisms of Fibrosis and Potential Antifibrotic Agentsp. 132
Mechanisms of Pain and its Medical Management, Including Neurolytic Treatmentsp. 140
Endoscopic Treatment of Pain and Complications of Chronic Pancreatitisp. 146
Surgical Treatment of Chronic Pancreatitisp. 155
Cystic Fibrosis
Genetics and Molecular Pathology of Cystic Fibrosisp. 167
Treatment of Gastrointestinal Manifestations in Cystic Fibrosisp. 180
Is Idiopathic Chronic Pancreatitis Cystic Fibrosis?p. 193
Pancreatic Cancer
Growth Factors and Transcription Factors in Pancreatic Cancerp. 205
Biological Approaches to the Therapy of Pancreatic Cancerp. 222
Pancreatic Cancer: Preclinical Development of an Experimental Treatment Strategy Using Retinoids and Interferon-alphap. 230
Aspects of Radical Surgery for Exocrine Cancer of the Pancreatic Headp. 238
Epidemiology
Lessons Learned about Pancreatitis and Pancreatic Cancer from Epidemiological Studiesp. 253
Subject Indexp. 263
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9783540653578
ISBN-10: 3540653570
Audience: General
Format: Paperback
Language: English
Number Of Pages: 272
Publisher: Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
Country of Publication: DE
Dimensions (cm): 23.39 x 15.6  x 1.52
Weight (kg): 0.41