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Pain Mechanisms and Management - A.V. Apkarian

Pain Mechanisms and Management

By: A.V. Apkarian (Editor), S. Ayrapetian (Editor)

Hardcover

Published: 1st January 1997
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The overall themes of this book are recent advances in mechanisms of pain and the application of those in clinics. Specific attention is paid to developing countries where practice of pain management seriously lags behind current scientific understanding. Both the local traditions for curing pain and the substances used are presented in this book.

Foreword
Preface
Salutatory Address
Opening Address
Metabolic Regulation of the Neuron
The Application of the Theory of Metabolic Regulation to Painp. 3
Effects of Metabolic Disruption on Neuronal Excitabilityp. 15
Signal Transduction Mechanism and Metabolic Regulation of Axoplasmic Transport in Superior Cervical Ganglion Cellsp. 29
Molecular and Cellular Mechanisms in Neurotransmitter Releasep. 35
Peripheral and Spinal Cord Physiology
Nociceptive Pain Mechanisms and Chronificationp. 51
The Spinal Rat: A Model System for Studying the Behavioral Pharmacology of Spinal Nociceptive Reflexesp. 59
Spinal Facilitation and the Post Tissue Injury Pain Statep. 71
Changes in Nociceptive Processing in the Setting of Persistent Injury: Insights from an Analysis of the Interaction of Substance P with its Receptor in the Rat Spinal Cordp. 79
Morphine and Noxiously Evoked Spinal Fos Expression Induced by Carrageenin Inflammationp. 88
The Role of Signal Transduction Pathways in Sensitization of Primate Spinothalamic Tract Neuronsp. 106
Dissociation between Peripheral and Central Components of the Endotoxin-Induced Hyperalgesiap. 120
Thymulin at High Doses Reduces Endotoxin-Induced Hyperalgesia by Reducing Interleukin-1[beta] and Nerve Growth Factor Levels in the Hind Paw of Ratsp. 131
The Effect of Diet on Neuropathic Pain Expression in Ratsp. 139
Supraspinal Physiology
Manifestations and Mechanisms of Painp. 159
A Possible Involvement of Meso-Striato-Limbic Structures in Pain Modulationp. 164
Neuronal Organization of Limbic Mechanisms of Pain Sensitivity Regulationp. 181
The Endogenous Pain Control System: Facilitating and Inhibitory Pathwaysp. 192
Thalamocortical Connections of the Cingulate and Insula in Relation to Nociceptive Inputs to the Cortexp. 212
Measurement of Tonic Pain in Animals by Evoked Potentialsp. 221
Pain Perception and the Role of Thalamocortical Inhibitory Networks across Organizational Scalesp. 228
Neurotransmitter Receptor Mechanisms Involved in Nociceptive Processing in the Thalamusp. 237
The Mechanisms by which Tissue Damage and Pain are Relatedp. 252
Magnetic Transcranial Stimulation Studies in Humans on the Roles of Frontal and Occipital Lobes in Perception, on Estimating Perceptual Delay, and on Temporary Pain Relief with Parietal Stimulationp. 260
Pharmacology
Design of Novel Nicotinic Acetylcholine Receptor Agonists with Potential Antinociceptive Activityp. 285
Low and High Molecular Compounds from Plants and Animals with Antiinflammatory Activity - A Survey of Results from a 10 Year Screening Programp. 301
Arachidonic Acid Release and Metabolism Associated Mode of Action of Some Plant Immunomodulatorsp. 308
Review of the Medicinal Plants of Armenia and Karabaghp. 319
Locust Poison (LP) as Pain Relieving Drugp. 322
Halothane Anaesthesia in Molecular Mechanism of Oxidative Stress Pathogenesisp. 330
Cellular and Molecular Mechanisms of Nitric Oxide Effectsp. 335
Pain Management (Social Issues)
The Tropho-Defensive System (T-DS) as Target to Prevent Chronic Pain in Orthopedics, Traumatology and Rheumatologyp. 355
Pain Management in the Republic of Nagorno-Karabaghp. 360
Pain Management in Armeniap. 364
Pain Perception in War and Disease: An Epidemiologic Outlookp. 369
Pain Management (Clinical Issues)
Percutaneous Radiofrequency Nucleotomy in Symptomatic Disc Protrusionp. 377
CT-Controlled Instillation of Tramadol, Cortison and Lidocaine - a Comparative Studyp. 381
Computertomographic Guided Percutaneous Interventions for Chronic Pain Treatmentp. 383
Computertomographic Controlled Epidurography for Safe Epidural Blockadesp. 386
Author Indexp. 389
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9789051993066
ISBN-10: 9051993064
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 408
Published: 1st January 1997
Publisher: IOS Press
Country of Publication: US
Dimensions (cm): 23.4 x 15.6  x 2.3
Weight (kg): 0.75
Edition Number: 1