BL Clear, experimental details in a convenient format BL Practical advice from experienced researchers BL Tried and tested methods This new book launches the Practical Approach Series in Chemistry, especially for chemists who require practical and expert guidance on all aspects of chemical technique to achieve the best results - fast. This essential laboratory handbook
dispels the mystery surrounding organocopper compounds, and offers expert guidance on how to overcome the many problems associated with their use. Clear, practical procedures for the preparation and
application of these highly specific reagents are described in detail by leading researchers. Organocopper Reagents: A Practical Approach is a comprehensive laboratory guide which will prove invaluable to all organic chemists wishing to use copper reagents in synthesis. Both new and established researchers will find in this book all the information they need to enable them to exploit these powerful synthetic reagents to maximum effect.
`It has been a pleasure to review this excellent volume. It will prove to be of value to academic and industrial practitioners of organic synthesis. I confidently expect that all reasearch laboratories will contain a copy. I hope that the publishers will be persuaded to standardise the drawings in future volumes - there are even differences within some chapters - so as to achieve a uniformity of presentation. Despite this minor criticism, all those
connected with the production of this book are to be congratulated.'
Harry Heaney, Chemistry & Industry
The good working procedures to be found in this book should make it possible to overcome all hesitation in using organometalic or organocopper reagents. The instructions are so detailed (apparatus, reaction conditions, preparation) that even a beginner in organic chemistry should hardly have any difficulties in follwing them. All important aspects of modern organocopper chemistry are dealt with in detail. s
`This is an excellent reference book that provides very detailed experimental procedures and expert commentary by the current leading researchers in this field of organocopper chemistry.'
`...this is an extraordinarily useful book for the preparative organic chemist. Written by world-famous specialists, it offers easy access to organocopper chemistry. It should be available in every library.'
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`Authoritative, comprehensive, well documented account of the title subject. The format, presentation and even the price make this a highly recommendable first text in a new series.'
Aslib Book Guide, Vol. 60, No. 8, August 1995
1: R.J.K. Taylor: Organocopper chemistry: an overview
2: R.J.K. Taylor and G. Casy: General procedures: starting materials and reaction guidelines
3: R.D. Rieke and W. R. Klein: Preparation of reagents using activated copper
4: P. Knochel, M. J. Rozema, and C. E. Tucker: Preparation of highly functionalized reagents
5: B.H. Lipschutz: Higher order cuprates
6: E. Nakamura: Me3SiCl accelerated conjugate additions
7: Y. Yamamoto and T. Ibuka: BF3/AlCl3 mediated conjugate addition and substitution reactions
8: A. Alexakis: Asymmetric conjugate addition
9: M. Suzuki and R. Noyori: Conjugate addition - enolate trapping reactions
10: I. Campbell: Sonogashira Cu/Pd catalysed alkyne coupling
11: J.F. Normant: Alkyne carbocupration and polyene synthesis via palladium catalysed coupling
12: I. Fleming: Synthetic applications of silyl and stannyl cuprates
13: R.A.J. Smith: Mechanistic studies of organocopper reactions
R.J.K. Taylor and J.M. Herbert: Appendix 1: Compilation of organocopper preparations
Appendix 2: Suppliers of reagents and specialist items