Optical Imaging of Brain Function and Metabolism

By: Ulrich Dirnagl, K. M. Einhc$upl (Editor)

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Hardcover | 31 July 1993

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Hardcover
312 Pages

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25.4 x 17.78 x 1.91

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• . . . . At last the doctor will be freed from the tedious interpretation of screens and photographs. Instead, he will examine and scan through his patient directly. Wearing optical-shutter spectacles and aiming a pulsed laser torch, he will be able to peer at the beating heart, study the movement of a joint or the flexing of a muscle, press on suspect areas to see how the organs beneath respond, check that pills have been correctly swallowed or that an implant is savely in place, and so on. A patient wearing white cotton or nylon clothes that scatter but hardly absorb light, may not even have to undress . . . . •. David Jones, Nature (1990) 348:290 Optical imaging of the brain is a rapidly growing field of heterogenous techniques that has attracted considerable interest recently due to a number of theoretical advantages in comparison with other brain imaging modalities: it uses non ionizing radiation, offers high spatial and temporal resolution, and supplies new types of metabolic and functional information. From a practical standpoint it is important that bedside examinations seem feasible and that the implementations will be considerably less expensive compared with competing techniques. In October 1991, a symposium was held at the Eibsee near Garmisch, Germany to bring together the leading scientists in this new field.

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You Can Find This Book In

Non-Fiction Engineering & Technology Technology in General Medicine Clinical & Internal Medicine Neurology & Clinical Neurophysiology Science Biology, Life Sciences Zoology & Animal Sciences Other Branches of Medicine Medical Imaging Physics

Applied Physics Biophysics Surgery Neurosurgery

NMR and time-resolved optical studies of brain imaging	p. 1
Wavelength dependence of the differential pathlength factor and the log slope in time-resolved tissue spectroscopy	p. 9
Towards human brain near infrared imaging: Time resolved and unresolved spectroscopy during hypoxic hypoxia	p. 21
Measurement of human hypothermic cerebral oxygen metabolism by transmission spectroscopy	p. 33
Optical CT imaging of hemoglobin oxygen-saturation using dual-wavelength time gate technique	p. 43
Optical properties of normal human intracranial tissues in the spectral range of 400 to 2500 nm	p. 47
Optical imaging of the functional architecture in cat visual cortex: The layout of direction and orientation domains	p. 57
Mapping of neural activity patterns using intrinsic optical signals: From isolated brain preparations to the intact human brain	p. 71
Fiber optic imaging of subcortical neural tissue in freely behaving animals	p. 81
Olfactory information processing in insects revealed by real-time optical imaging of intrinsic signals	p. 87
Infrared imaging of brain function	p. 95
IR thermal imaging of a monkey's head: Local temperature changes in response to somatosensory stimulation	p. 125
Spatiotemporal inhomogeneity of [Ca][subscript i] in neurons	p. 137
Intracellular ion concentrations in the brain: approaches towards in situ confocal imaging	p. 145
Optical access to the brain: how artificial are cranial window techniques?	p. 177
Multiparametric imaging of microregional circulation over the brain cortex by videoreflectometry	p. 183
Towards imaging of cerebral blood flow and metabolism on a microscopical scale in vivo	p. 193
Detection of brain free oxygen radical generated photons in vivo: Preliminary results	p. 203
Diffusion properties of brain tissue measured with electrode methods and prospects for optical analysis	p. 213
Measuring oxygen using oxygen dependent quenching of phosphorescence: A status report	p. 225
Laser fluorescence spectroscopic experiments for monitoring molecules in brain	p. 233
Infrared-interference videomicroscopy of living brain slices	p. 245
Blood-brain barrier transport measurements using PET-scanning and intravenous double indicator technique	p. 251
Nuclear magnetic resonance studies of human brain in vivo: Anatomy, function, and metabolism	p. 257
Autoradiographic and biochemical imaging in cerebral ischemia	p. 273
Contributors	p. 287
Index	p. 293
Table of Contents provided by Blackwell. All Rights Reserved.

Optical Imaging of Brain Function and Metabolism

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