Beginning with a concise review of the biological roles of nucleic acids, the text then discusses the components from which they are made, and works up through nucleosides and nucleotides to the covalent structures of the nucleic acids themselves. The double helical structure of DNA and its implications for replication are then described.
This is followed by a detailed treatment of the chemistry of the processes by which the information encoded in DNA is expressed in terms of the amino acid sequences of proteins. The final chapter describes modern tools of DNA analysis and how they have been used in a range of recent applications such as gene cloning, genome sequence analysis, and DNA fingerprinting.
The book provides a lot of information on the various aspects of nucleic acids in a concise and nicely written manner that makes it a very good read. * Analytical and Bioanalytical Chemistry, (2006), 385: 10-11 (Jorg D Hoheisel) *
Highly recommended for undergraduate students in chemistry and related fields * Carbohydrate Polymers, 58 (2004), 483-485 (John F Kennedy) *