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Nicotinoid Insecticides and the Nicotinic Acetylcholine Receptor - I. Yamamoto

Nicotinoid Insecticides and the Nicotinic Acetylcholine Receptor

By: I. Yamamoto (Editor), John E. Casida (Editor)

Hardcover

Published: August 1999
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The nicotinoids are the most important new class of pesticides, joining the organophosphorus compounds, methylcarbamates, and pyrethroids as the major insecticides. Recently, imidacloprid and related nicotinoids have begun replacing organophosphorus and methylcarbamate compounds as insecticides to control insect pests on major crops. Nicotinoids act on the nicotinic acetylcholine receptor, as does naturally occurring nicotine, but with remarkable effectiveness against insects while being safe for mammals; they are quickly degraded and do not persist in the environment. This volume describes the relationship of nicotinoids to botanical insecticidal alkaloids, their discovery and development as insecticides, and the prospects for their expanded use and for the development of resistance. This book is the first to provide concise, comprehensive information on nicotinoids, their chemistry, mode of action, metabolism, and application in agriculture.

Preface
Nicotine to Nicotinoids
Nicotine to Nicotinoids: 1962 to 1997p. 3
Nicotine and Other Insecticidal Alkaloidsp. 29
Discovery of the Nitromethylene Heterocycle Insecticidesp. 71
Discovery of Chloronicotinyl Insecticidesp. 91
Synthetic Nicotinoid Insecticides
Chloronicotinyl Insecticides: A Success of the New Chemistryp. 109
Discovery of a New Systemic Insecticide, Nitenpyram and Its Insecticidal Propertiesp. 127
A Novel Insecticide, Acetamipridp. 149
CGA 293'343: A Novel, Broad-Spectrum Neonicotinoid Insecticidep. 177
Nicotinoid Insecticide Toxicology
Imidacloprid: Toxicology and Metabolismp. 213
The Action of Nicotine in the Mammalian Brainp. 223
Nicotine Analogs: Structure-Affinity Relationships for Central Nicotinic Acetylcholinergic Receptor Bindingp. 237
Managing Resistance to the Chloronicotinyl Insecticides-Rhetoric or Reality?p. 253
Structure and Function of Insect Nicotinic Acetylcholine Receptors Studied with Nicotinoid Insecticide Affinity Probesp. 271
Indexp. 293
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9784431702139
ISBN-10: 443170213X
Audience: General
Format: Hardcover
Language: English
Number Of Pages: 300
Published: August 1999
Publisher: Springer Verlag, Japan
Country of Publication: JP
Dimensions (cm): 23.5 x 15.5  x 2.16
Weight (kg): 0.69