Nicotine in the form of tobacco has been more widely used by man than any other psychoactive drug. This is a collection of reviews by experts, on many aspects of the psychopharmacology of nicotine, integrating the present state of knowledge gained from a variety of different approaches. Recognition of the important role of nicotine in tobacco addiction, together with rapid advances in the techniques available to neuroscientists, has led to a great increase in research into the effects of nicotine on the central nervous system. This book presents the latest contributions of molecular, biochemical, neurophysiological and behavioural approaches to studying nicotine and central nicotinic receptors. As well as having implications for health problems associated with tobacco use, the results have enhanced understanding of how central nicotinic mechanisms are involved in other psychiatric and neurological states, such as Parkinson's Disease and Alzheimer's Disease.
` This book is a must for anyone working in this field.' Journal of Smoking Related Disorders and also Journal of Drug Development
'This book is unique in providing a comprehensive and readable account of the state of knowledge......This book is particularly strong in the uniformly high quality of the contributions' TiPS
'This book is a thorough, up-to-date summary of the diverse areas of scientific knowledge about nicotine. It is an invaluable reference text for students and researchers interested in the cholinergic system.'
Gemma M.M. Jones, Institute of Psychiatry, London, International Journal of Geriatric Psychiatry, 6:9
Jerome H. Jaffe: Tobacco, smoking, and nicotine dependence; Michael D.B. Swedburg, Jack E. Henningfield, & Steven R. Goldberg: Evidence of nicotine dependency from animal studies: self-administration, tolerance, and withdrawal; David M. Warburton: Psychopharmacological aspects of nicotine; Neal L. Benowitz, Herve Porchet, & Peyton Jacob: Pharmacokinetics, metabolism, and pharmacodynamics of nicotine; Paul B.S. Clarke: The central pharmacology of
nicotine: electrophysiological approaches; Kjell Fuxe, Kurt Andersson, Anders Härfstrand, Peter Eneroth, Miguel Perez de la Mora, & Luigi F. Agnati: Effects of nicotine on synaptic transmission in the brain; S.
Wonnacott: Characterization of nicotine receptor sites in the brain; I. P. Stolerman: Behavioural pharmacology of nicotine in animals; C. Reavill: Actions of nicotine on dopamine pathways and implications for Parkinson's disease; Kenneth J. Kellar & S. Wonnacott: Nicotinic-cholinergic receptors in Alzheimer's disease; M.A.H. Russell: Nicotine intake and its control over smoking; Index.
Series: Oxford Science Publications
Number Of Pages: 446
Published: 3rd May 1990
Country of Publication: GB
Dimensions (cm): 24.13 x 16.2
Weight (kg): 0.92