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New Aspects of Axonal Structure and Function - Joachim Luebke

New Aspects of Axonal Structure and Function

By: Joachim Luebke (Editor), Dirk Feldmeyer (Editor)

Hardcover

Published: 31st August 2010
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Axons are neuronal output elements and are responsible for the transfer and processing of signals from one neuron to another, even over very large distances. For a given neuronal cell type, axons are unique and display very heterogeneous patterns with respect to shape, length and target structure. Axons are the usually long process of a nerve fiber that generally conducts impulses away from the body of the nerve cell. This book is intended to summarize recent findings covering morphological, physiological, developmental, computational and pathophysiological aspects of axons. It attempts to cover new findings concerning axonal structure and functions together with their implications for signal transduction, processes implicated in the formation of axonal arbors and the transport of subcellular elements to their targets, and finally how a dysfunction in one or several of these steps could lead to axonal degeneration and ultimately to neurodegenerative diseases.

Axons in Development
Molecular Aspects of Commissural Axon Guidancep. 3
Subplate and the Formation of the Earliest Cerebral Cortical Circuitsp. 19
Axonal Function
Sodium Signals and Their Significance for Axonal Functionp. 35
New Insights in Information Processing in the Axonp. 55
Electrical Coupling of Axonsp. 85
To Myelinate or Not to Myelinate?p. 103
Axons and Neuronal Circuits
An Axonal Perspective on Cortical Circuitsp. 117
Axons Predict Neuronal Connectivity Within and Between Cortical Columns and Serve as Primary Classifiers of Interneurons in a Cortical Columnp. 141
The Axon of Excitatory Neurons in the Neocortex: Projection Patterns and Target Specificityp. 157
Axons and Degeneration/Regeneration
Axon Degeneration: Mechanisms and Consequencesp. 181
Regeneration After CNS Lesion: Help from the Immune System?p. 209
Indexp. 233
Table of Contents provided by Ingram. All Rights Reserved.

ISBN: 9781441916754
ISBN-10: 144191675X
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 237
Published: 31st August 2010
Publisher: Springer-Verlag New York Inc.
Country of Publication: US
Dimensions (cm): 23.5 x 15.5  x 1.91
Weight (kg): 0.6