Neuroscientific Basis of Dementia - Chikako Tanaka

Instant online reading.
Don't wait for delivery!
Go digital and save!

Neuroscientific Basis of Dementia

By: Chikako Tanaka (Editor), Patrick L. McGeer (Editor), Yasuo Ihara (Editor)

Write A Review

Hardcover | 1 December 1999

At a Glance

Hardcover
324 Pages

Dimensions(cm)
23.5 x 16.51 x 1.91

Hardcover

$139.00

or 4 interest-free payments of $34.75 with

Ships in 7 to 10 business days

This volume presents both an overall and a detailed overview of the current worldwide knowledge about the neuroscientific basis of dementia.
Leading authorities in their fields provide a far-reaching synthesis of all topics in dementia research, including pathogenesis of dementia, neuroimaging of the earliest alterations, potential biological and genetic markers for Alzheimer's Disease and new therapeutic strategies. Each chapter discusses clinical implications and areas of controversy, highlights the wide range of current and future therapeutic possibilities and indicates promising directions for further research.
The book will be of high value not only to scientists and graduate students in medical, pharmacological and biological research, but also to physicians and researchers in the biotechnological and pharmaceutical industries.

Shipping

	Standard Shipping	Express Shipping
Metro postcodes:	$9.99	$14.95
Regional postcodes:	$9.99	$14.95
Rural postcodes:	$9.99	$14.95

Orders over $79.00 qualify for free shipping.

How to return your order

At Booktopia, we offer hassle-free returns in accordance with our returns policy. If you wish to return an item, please get in touch with Booktopia Customer Care.

Additional postage charges may be applicable.

Defective items

If there is a problem with any of the items received for your order then the Booktopia Customer Care team is ready to assist you.

For more info please visit our Help Centre.

You Can Find This Book In

Non-Fiction Medicine Clinical & Internal Medicine Neurology & Clinical Neurophysiology Science Biology, Life Sciences Life Sciences in General Neurosciences Other Branches of Medicine Pharmacology Clinical Psychology Zoology & Animal Sciences

List of contributors
Preface
A tale of protein kinase C and membrane lipid signaling	p. 3
Complement, neuroinflammation and neuronal degeneration in Alzheimer disease	p. 15
Neurobiological mechanisms by which emotional arousal influences long-term memory formation	p. 23
Amygdalar damage and memory impairment in Alzheimer's disease	p. 35
Neural substrate for spatial memory in the monkey hippocampus	p. 43
Involvement of CaM kinase II and mitogen-activated protein kinase in hippocampal long-term potentiation	p. 49
Transgenic mice overexpressing the shortest human tau isoform develop a progressive tauopathy	p. 61
Tau and neurodegenerative disease: genetics and pathogenetic mechanisms	p. 71
The mutations altering splicing of tau exon 10 in japanese frontotemporal dementia	p. 81
Amyotrophic lateral sclerosis/parkinsonism-dementia complex of the Kii peninsula of Japan (Kii ALS/PDC) may be a familial tauopathy, Epidemiological trends, clinical features, neuropathology and molecular genetics	p. 85
Senile dementia of the neurofibrillary tangle type (SD-NFT): a clinical, neuropathological and molecular genetic study	p. 95
The dual role of tau in cell polarisation and organelle trafficking	p. 101
Rearrangement of microtubule networks by tau bearing missense mutations	p. 113
Possible role of tau phosphorylation on ER membrane in Alzheimer patholoy	p. 121
Pathogenesis of dementia: updating the role of synuclein pathology in sporadic and hereditary Alzheimer's disease	p. 131
[alpha]-Synuclein/NACP and neurodegeneration	p. 137
[alpha]-Synuclein fibrillogenesis as target for drug development	p. 143
Genetics of early-onset Alzheimer disease	p. 153
Lessons from presenilin domain analysis: endoproteolytic processing and enhanced A[beta]42 production mediated by FAD-linked variants	p. 167
Amyloid and presenilins in the pathobiology of Alzheimer's disease	p. 177
Role of presenilin in APP processing and A[beta] production	p. 183
Impairment of response to ER stress in presenilin 1 mutant	p. 193
Mechanism of neuron death in Alzheimer's disease	p. 201
Notch3 gene in CADASIL syndrome: mutation frequencies in Japanese and its expression and processing	p. 209
Etiological roles of A[beta] and carboxyl terminal peptide fragments of amyloid precursor protein in Alzheimer disease	p. 217
Amyloid [beta]-protein granules in glial cells in Alzheimer's disease brain	p. 225
Amyloid [beta] induces phosphorylation and translocation of MARCKS through tyrosine kinase-activated PKC-[delta] signaling pathway in microglia	p. 229
Amyloid [beta]-protein accumulation in the human brain during aging	p. 233
Molecular mechanisms underlying initiation of amyloid fibril formation	p. 241
Catabolism of amyloid-[beta] peptide in brain parenchyma	p. 249
Lessons in familial Alzheimer's disease	p. 259
Biological markers for differential diagnosis of Alzheimer's disease and related disorders	p. 267
Dietary factors and the risk of Alzheimer's disease: a low fish consumption and a relative deficiency of [omega]-3 polyunsaturated fatty acids	p. 275
Risk factors for dementia	p. 279
New therapeutic approaches to Alzheimer's disease	p. 287
Subject index	p. 295
Table of Contents provided by Blackwell. All Rights Reserved.

Neuroscientific Basis of Dementia

At a Glance

Hardcover

Shipping

How to return your order

Defective items

You Can Find This Book In

More in Clinical Psychology

Issues and Ethics in the Helping Professions

11th Cengage International Edition

DBT Skills Training Handouts and Worksheets

2nd Edition

The Skilled Helper 11ed

A Problem-Management and Opportunity-Development Approach to Helping

Eye Movement Desensitization and Reprocessing (EMDR) Therapy

Basic Principles, Protocols, and Procedures 3rd Edition

The Handbook of Adult Clinical Psychology

2nd Edition - An Evidence Based Practice Approach

Mind Over Mood

2nd Edition - Change How You Feel by Changing the Way You Think

Experiencing CBT from the Inside Out

A Self-Practice/Self-Reflection Workbook for Therapists

Theory and Practice of Counseling and Psychotherapy

11th Edition

Psychology - Australian and New Zealand Edition

4th Edition

SPSS Statistics

5th Edition - A Practical Guide

Diagnostic and Statistical Manual of Mental Disorders 5/e TR (DSM-5-TR)

Diagnostic and Statistical Manual of Mental Disorders

Intentional Interviewing and Counseling

10th Edition - Facilitating Client Development in a Multicultural Society

Basic Personal Counselling

9th Edition - A Training Manual for Counsellors

Life Span Human Development

4th Edition

Theoretical Perspectives for Direct Social Work Practice: 4th Edition

A Generalist-Eclectic Approach

Principles and Practice of Grief Counseling

3rd Edition

Act Made Simple

An Easy-To-Read Primer on Acceptance and Commitment Therapy

The Dialectical Behavior Therapy Skills Workbook

Practical DBT Exercises for Learning Mindfulness, Interpersonal Effectiveness, Emotion Regulation, and Distress Tolerance

The Body Keeps The Score

Mind, Brain and Body in the Transformation of Trauma

Trauma-Focused ACT

A Practitioner's Guide to Working with Mind, Body, and Emotion Using Acceptance and Commitment Therapy

Clinical Handbook of Psychological Disorders

A Step-by-Step Treatment Manual, 6th Edition

The Book You Wish Your Parents Had Read (and Your Children Will Be Glad That You Did)

THE #1 SUNDAY TIMES BESTSELLER

Polyvagal Exercises for Safety and Connection

50 Client-Centered Practices

Polyvagal Flip Chart

Understanding the Science of Safety (Norton Series on Interpersonal Neurobiology)

This product is categorised by