The book gives a survey on recent theoretical as well as experimental results on nanostructures in biological systems. Some possible applications will be given. In theoretical part, a unifying approach starting from the single-particle energy, deriving free energy of the system and determining the equilibrium by minimizing the free energy, is applied in describing electrical and elastic phenomena. This approach is basic, transparent and simple so that new and additional systems and interactions can be included by the readers. As the theoretical and the experimental work have been developed in the same process, they support each other in broadening the knowledge on the system. Potential use of this knowledge in clinically relevant phenomena such as hemostasis, inflammation and spreading of cancer will be presented. At the end some applications in nanotoxicology will be described such as the interactions between biological membranes and inorganic nanostructures.
"Nanostructures in Biological Systems is a marvelous scientific appraisal of the state of the art of membrane biophysics. By building a strong bridge between physics and biological sciences, the authors succeed in accomplishing something that is exceptionally rare in scientific literature. Enjoy to be introduced into the wonder world of biological surfaces and experience their continuous conversions, such as in the fusion of lipid vesicles or as observed in direct cell-to-cell communication."
- Prof. Michael Rappolt, University of Leeds, UK
"Nanostructures in Biological Systems will become a cornerstone reference for membrane biophysicists. It covers the gap between two scientific worlds: one originating from physics, focusing on model membrane systems with controlled composition and environment, and the second from biology, working with membranes from living cells. It introduces the readers to the complex but fascinating study of natural or model membrane systems and is a wonderful opportunity for both communities working in biophysics. They will gain a common knowledge in a field where interdisciplinarity should be highly valuable."
- Prof. Philippe Meleard, ENSC-Rennes, France
Introduction: Nanostructures and Nanoparticles in Biological Systems. Description of Systems Composed of Large Number of Constituents. Lipid Nanostructures. Physics of Lipid Micro- and Nanostructures. Nanotubes of Biological Membranes. Spherical Budding of Biological Membrane. Exogenous Membrane Attached Nanoparticles. Membrane Electrostatics. Membranous Nanostructures as in vivo Cell-to-Cell Transport Mechanisms. Lipid Vesicles and Cells as Tools in Nanotoxicity Studies.
Tertiary; University or College
Number Of Pages: 534
Published: 18th June 2015
Publisher: Pan Stanford Publishing Pte Ltd
Country of Publication: SG
Dimensions (cm): 22.9 x 15.2
Weight (kg): 0.89
Edition Number: 1