Impact of Recombinant DNA Technology and Protein Structure Determination on Past and Future Studies on Acetylcholinesterase | p. 1 |
Biosynthesis of the Molecular Forms of Acetylcholinesterase | p. 17 |
Binding of Asymmetric (A[subscript 12]) Acetylcholinesterase to C[subscript 2] Muscle Cells and to CHO Mutants Defective in Glycosaminoglycan Synthesis | p. 25 |
Subunit Assembly and Glycosylation of Mammalian Brain Acetylcholinesterase | p. 33 |
Molecular Organization of Recombinant Human Acetylcholinesterase | p. 39 |
Expression and Refolding of Functional Human Butyrylcholinesterase from E. coli | p. 49 |
Part 1: Genetic Variant of Human Acetylcholinesterase - Part 2: SV-40 Transformed Cell Lines, for Example COS-1, but Not Parental Untransformed Cell Lines, Express Butyrylcholinesterase (BCHE) | p. 53 |
Heterogeneity of the Silent Phenotype of Human Butyrylcholinesterase - Identification of Eight New Mutations | p. 61 |
Nematode Acetylcholinesterases: Several Genes and Molecular Forms of their Products | p. 65 |
Drosophila Acetylcholinesterase: Analysis of Structure and Sensitivity to Insecticides by In Vitro Mutagenesis and Expression | p. 75 |
Altered Form of Acetylcholinesterase in Insecticide-Resistant Houseflies (Musca domestica) | p. 83 |
PCR Generated Homologous DNA Probes and Sequence for Acetylcholinesterase Genes in Insect Pests | p. 87 |
Testicular Gene Amplification and Impaired BChE Transcription Induced in Transgenic Mice by the Human BChE Coding Sequence | p. 91 |
Three-Dimensional Structure of Acetylcholinesterase | p. 95 |
Sequence Alignment of Esterases and Lipases Based on 3-D Structures of Two Members of This Family | p. 109 |
Structural Analysis of Acetylcholinesterase Ammonium Binding Sites | p. 117 |
Structural Investigations of the Acetylcholinesterase | p. 121 |
Substrate-Selective Inhibition and Peripheral Site Labeling of Acetylcholinesterase by Platinum (Terpyridine) Chloride | p. 131 |
Cryptic Catalysis and Cholinesterase Function | p. 141 |
Influence of Ionic Composition of the Medium on Acetylcholinesterase Conformation | p. 149 |
Molecular Dissection of Functional Domains in Human Cholinesterases Expressed in Microinjected Xenopus Oocytes | p. 157 |
Acetylcholinesterase Catalysis - Protein Engineering Studies | p. 165 |
Site-Directed Mutagenesis of Functional Residues in Torpedo Acetylcholinesterase | p. 177 |
Structurally Important Residues in the Region SER91 to ASN98 of Torpedo Acetylcholinesterase | p. 185 |
A Model of Butyrylcholinesterase Based on the X-ray Structure of Acetylcholinesterase Indicates Differences in Specificity | p. 189 |
Molecular Models for Human AChE and its Phosphonylation Products | p. 195 |
Relationships Between Activity of Organophosphorus Inhibitors of Acetylcholinesterase and Accessibility of Phosphorus Atom as Estimated by Molecular Mechanics Calculations | p. 201 |
Factors Influencing Acetylcholinesterase Regulation in Slow and Fast Skeletal Muscles | p. 209 |
Compartmentalization of Acetylcholinesterase mRNA and Protein Expression in Skeletal Muscle In Vitro and In Vivo: Implications for Regulation at the Neuromuscular Junction | p. 217 |
Towards a Functional Analysis Cholinesterases in Neurogenesis: Histological, Molecular, and Regulatory Features of BChE from Chicken Brain | p. 223 |
Acetylcholinesterase as a Modulatory Neuroprotein and its Influence on Motor Control | p. 233 |
Different Influence of Inhibitors on Acetylcholinesterase Molecular Forms G1 and G4 Isolated from Alzheimer's Disease and Control Brains | p. 243 |
Acetylcholinesterase Inhibition by Novel Carbamates: A Kinetic and Nuclear Magnetic Resonance Study | p. 251 |
Experimental Acetylcholinesterase Autoimmunity | p. 261 |
Clinical Implications of Cholinesterase Aberrations in Syndromes of Hemopoietic Cell Division | p. 269 |
Acetylcholinesterase: A Pretreatment Drug for Organophosphate Toxicity | p. 277 |
Recommendations for Nomenclature in Cholinesterases | p. 285 |
Index | p. 289 |
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