Monoclonal Antibodies

Series Introduction Preface -- 1. Monoclonal Antibodies: New Horizons in the Treatment of Human Autoimmune Disease /William J. Koopman -- 2. Therapeutic Application of Monoclonal Antibodies in the Rheumatic Diseases /Edward V. Lally -- 3. Treatment of Patients with Rheumatoid Arthritis with Anti-CD4 Monoclonal Antibodies /Christian Herzog, Wolfgang Muller, Christoph Walker, and Werner J. Pichler -- 4. Human Monoclonal Autoantibodies /Susan Alpert Gale I, Edgar G. Engleman, and Steven K. H. Foung -- 5. Biologic Therapies for Rheumatoid Arthritis: Concepts from Considerations on Pathogenesis /Ian R. Mackay, Merrill J. Rowley, and Claude C. A. Bernard -- 6. Cellular and Molecular Interactions in the Induction of Inflammation in Rheumatic Diseases /Sharon M. Wahl -- 7 Interleukin-1 Inhibitors and Their Significance in Rheumatoid Arthritis /Gloria C. Higgins and Arnold E. Postlethwaite -- 8. Interleukins and Metalloproteinases in Arthritis /Gene DiPasquale -- 9. T Cell Cytokines as Immunomodulators of Arthritis Disease Pathology /Thomas F. Kresina and Donna J. Spannaus-Martin -- 10. Induction and Regulation of Arthritis by T Cell-Derived Collagen Binding Proteins /David E. Trentham -- 11. Experimental Arthritis: Importance of T Cells and Antigen Mimicry in Chronicity and Treatment /Wim B. van den Berg, Maries F. van den Broek, Levinus B. A. van de Putte, Mieke C. J. van Bruggen, and Peter L. E. M. van Lent -- 12. A Mycobacterial 65 kd Heat-Shock Protein and T Cells in Experimental Arthritis: Possibilities for Immunotherapy /Willem van Eden, Claire J. P. Boog, Els J. M. Hogervorst, Marca H. M. Wauben, Ruurd van der Zee, and Jan D. A. van Embden -- 13. Immunotherapy of Collagen-Induced Arthritis with Anti-la and Anti-IL-2R Antibodies /Paul H. Wooley and Subhashis Banerjee -- 14. Anti-L3T4 Antibody Therapy in Systemic Lupus Erythematosus /Nancy L. Carteron and David Wofsy -- 15. Autoreactive B Cells in Collagen-Induced Arthritis /Rikard Holmdahl -- 16. Antiproteoglycan Antibodies in Experimental Spondylarthritis /Tibor T. Giant, Katalin Mikecz, Edit Buzas, Eric Dayer, and A. Robin Poole -- 17. Reproduction and Regulation of the Autoimmunity That Induces Cartilage Pathology in Experimental Immune Synovitis /Thomas F. Kresina -- 18. Serum Keratan Sulfate Concentration as a Measure of the Catabolism of Cartilage Proteoglycans /Eugene J.-M. A. Thonar, James M. Williams, M. Barry E. Sweet, Brian A. Maldonado, Mary Ellen Lenz, Thomas J. Schnitzer, Giles V. Campion, and Klaus E. Kuettner -- 19. Cross-Reactive Idiotypes of Rheumatoid Factors in Arthritis and Related Diseases /Pojen P. Chen and Dennis A. Carson -- 20. Characterization of Rheumatoid Factors Using Monoclonal Anti-idiotypic Reagents /Mary Ann Accavitti, Ralph E. Schrohenloher, and William J. Koopman -- 21. The Human Anti-DNA Idiotype (16 /6 Idiotype) /Howard Amital-Teplizki and Yehuda Shoenfeld -- 22. Immunoregulation in Systemic Lupus Erythematosus by Idiotypic Network: Possible Future Therapeutic Implications /Nabih /. Abdou and Ronsuke Suenaga -- 23. Clinical Trial Design and Concepts for Biologic Agents in the Treatment of Rheumatic Diseases /Vibeke Strand -- Index.