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Molecular Mechanisms Of Drug Action - Christopher J. Coulson

Molecular Mechanisms Of Drug Action

Hardcover Published: 3rd February 1994
ISBN: 9780748400683
Number Of Pages: 300

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In this book the targets of drug action are the central focus - whether they be enzymes in a pathway or membrane-bound receptors and ion channels. This approach distinguishes the book from others in the f ield which consider the subject mainly in terms of disease.; The introductory chapter is concerned with the basic principles that cover enzyme inhibition and receptor binding by drugs. The next seven chapters deal with drugs that modulate biochemical pathways, both of synthesis and breakdown, while the last four chapters are concerned with organizational structures of the cell.; The book brings together the state of knowledge with respect to drug action and emphasizes mechanistic aspects of drug action. It encompasses the modes of action of drugs for infectious disease and those for endogenous conditions. There is a listing of reviews and essay questions are provided for each chapter.

General principles
nucleic acid biosynthesis and catabolism
protein biosynthesis
carbohydrate metabolism
cell wall biosynthesis
steroid biosynthesis and action
prostaglandin and leukotriene biosynthesis and action
zinc metalloenzymes
neurotransmitter action and metabolism; membrane active agents
microtubule assembly; hormonal modulators
Appendix: quantification of ligand/macromolecule binding
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780748400683
ISBN-10: 0748400680
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 300
Published: 3rd February 1994
Publisher: Taylor & Francis Ltd
Country of Publication: GB
Dimensions (cm): 23.5 x 15.6  x 2.0
Weight (kg): 0.65
Edition Number: 2
Edition Type: New edition