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Molecular Biology of Membranes : Structure and Function - H.R. Petty

Molecular Biology of Membranes

Structure and Function

Hardcover Published: 31st May 1993
ISBN: 9780306444296
Number Of Pages: 404

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This text attempts to introduce the molecular biology of cell membranes to students and professionals of diverse backgrounds. Although several membrane biology books are available, they do not integrate recent knowledge gained using modern molecular tools with more traditional membrane topics. Molecular techniques, such as cDNA cloning and x-ray diffraction, have provided fresh insights into cell membrane structure and function. The great excitement today, which I attempt to convey in this book, is that molecular details are beginning to merge with physiological responses. In other words, we are beginning to understand precisely how membranes work. This textbook is appropriate for upper-level undergraduate or beginning graduate students. Readers should have previous or concurrent coursework in biochemistry; prior studies in elementary physiology would be helpful. I have found that the presentation of topics in this book is appropriate for students of biology, biochemistry, biophysics and physiology, chemistry, and medicine. This book will be useful in courses focusing on membranes and as a supplementary text in biochemistry courses. Professionals will also find this to be a useful resource book for their personal libraries.

An Introduction to Biological Membranes
Lipids, Oligomers, and Proteins
Membrane Lipidsp. 7
Oligomeric Membrane Ionophoresp. 20
Membrane Proteinsp. 26
Carbohydrates and Cytoskeletal Components
Membrane Carbohydratesp. 51
Membrane Skeletonsp. 60
Supramolecular Membrane Structure
X-ray and Electron Diffraction and Image Processingp. 85
Transmission Electron Microscopyp. 102
Scanning Electron Microscopyp. 113
Bioenergetics: Putting Membranes to Work
The Importance of Proton Pumpingp. 123
Photosynthetic Membranesp. 129
Mitochondrial Membranes: The Respiratory Chainp. 164
The Payoff: Transducing Proton Potential into ATPp. 178
Transport Across Membranes
Molecular Transportp. 189
Macromolecular and Bulk Transportp. 210
Receptors and Responses
Receptors: An Introductionp. 223
Channel Receptors: The Nicotinic Acetylcholine Receptorp. 228
RGC Receptors: The [beta]-Adrenergic Receptorsp. 236
Polypeptide Hormone Receptors: The Insulin Receptorp. 254
Adherence Receptorsp. 273
A Survey of Signaling Strategies and Their Cytoskeletal Communicationp. 282
Membrane Fusion, Formation, and Flow
Fusionp. 297
Biosynthesis of Membrane Lipids, Proteins, and Carbohydrates and Their Translocation across Membranesp. 302
Biosynthetic Membrane Flowp. 330
Membranes in Cancer
Phenotypic Properties of Cancer Cells and Their Membranesp. 353
Aberrant Membrane Signals of Oncogene Products Potentiate Cell Growthp. 358
Expression of Membrane P-glycoproteins Allows Cancer Cells to Evade Chemotherapyp. 367
Role of Membranes in Metastasis and Invasionp. 368
Tumor-Specific Antigensp. 371
Indexp. 379
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9780306444296
ISBN-10: 0306444291
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 404
Published: 31st May 1993
Publisher: Springer Science+Business Media
Country of Publication: US
Dimensions (cm): 26.04 x 17.78  x 2.54
Weight (kg): 0.93

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