The science of blood groups was born at the beginning of this century, when the field of immunology married that of genetics. Most of the subsequent progress in immunogenetics was achieved by British investigators. The six consecutive editions of the unequaled Blood Groups in Man have long been considered as the bible of blood groupers. It is quite unfortunate that this book has not been revisited since 1975. Although one cannot do without immunogenetics, which remains useful for the identification of new blood groups and genetic studies, the focus of interest has moved somewhat today. After several decades, the molecular basis of blood groups can be investigated by biochemists. From 1950 to 1980, the ABO, Hh, and Lewis blood groups served as models and their chemical basis came to be established. The red cell membrane glycophorins carrying the MN and Ss antigens and the glycolipids with P blood group specificities were also identified and characterized. The chemical basis of the other groups, however, remained largely unknown.
`This significant and valuable book is a volume of a great series....All contributors are strongly involved experts and leading authorities in their field....Highly useful for all clinicians and researchers.'
International Journal of Hematology
`Provide[s] a comprehensive account of the biology of blood cells....a valuable overview of the subject...A strong case can be made for the purchase of the series by appropriate libraries.'
Trends in Biological Sciences, from a review of a previous volume
Red Cell Membrane: Structure, Function, Aging; J. Delaunay. ABO Hh, Lewis and Secretion: Serology, Genetics and Tissue Distribution; R. Oriol. Biochemistry and Biosynthesis of ABH and Lewis Antigens: Characterization of Blood Group Specific Glycosyltransferases; J.B. Lowe. Serology, Biochemistry, and Pathology of Antigens Defined by Cold Agglutinins; D. Roelcke. MNSs Blood Groups and Major Glycophorins; C.H. Huang, O. Blumenfeld. Rh Blood Group and Rhnull Syndrome; J.P. Cartron, P. Agre. Kell Blood Group and McLeod Syndrome; C. Redman. Duffy Blood Group and Malaria: Serology, Genetic, and Biochemistry; O. Pogo. Kidd Blood Group and Urea Transport; J. Moulds. Lutheran Antigens and Cell Surface Proteins Regulated by Lutheran Regulatory Genes; M. Telen. P Blood Groups: Serology, Genetic, Biochemistry, Receptors for Parasites; P. Bailly, J.F. Bouhours. Gerbich Blood Groups and Minor Glycophorines; Y. Colin, C. Le Van Kim. Overview of Other Blood Group Systems; P. Tippett. Blood Group Antigens as Markers of Complement and Complement Regulatory Molecules; G. Daniels. 4 additional articles. Index.
Series: Language of Science
Number Of Pages: 492
Published: 31st January 1995
Publisher: SPRINGER VERLAG GMBH
Country of Publication: US
Dimensions (cm): 25.4 x 17.78
Weight (kg): 0.88