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Modern Immunosuppressives

By: H.-J. Schuurman (Editor), G. Feutren (Editor), J.-F. Bach (Editor)

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Hardcover | 1 August 2001

At a Glance

Hardcover
236 Pages

Dimensions(cm)
23.5 x 17.15 x 1.91

Hardcover

$139.00

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Expanding from the classic use of immunosuppressants in transplantation and rejection, this current overview highlights their new roles in clinical medicine. Immunosuppressants are at the forefront of new treatment modalities. Individual chapters focus on their use not only in prevention or treatment of transplant rejection, but also on their use in immune-complex and autoimmune diseases, including rheumatoid arthritis; on combination therapies to achieve synergy in immunosuppression; on new drugs, low molecular weight chemicals, the use of antibodies and gene therapy; on immunological tolerance to prevent or inhibit transplant rejection; and how data derived from transplant studies can be applied to other avenues of immunosuppression. Clinicians and researchers will appreciate the scope of the work and the presentation of new approaches in the rapidly developing field of immunosuppression.

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Non-Fiction Medicine Clinical & Internal Medicine Diseases & Disorders Immunology Science Biology, Life Sciences Surgery Transplant Surgery Other Branches of Medicine Pharmacology Medicine in General

Abbreviations
List of contributors
Preface
Introduction, global perspectives and history of immunosuppression	p. 1
Cyclosporine: role of pharmacokinetics	p. 11
Tacrolimus	p. 29
The potential role of immunosuppressive macrocyclic lactones	p. 43
Inosine monophosphate dehydrogenase inhibition: mycophenolate mofetil	p. 77
Therapeutic anti-T-cell monoclonal antibodies	p. 99
Targeting the IL-2 receptor with antibodies or chimeric toxins	p. 115
Emerging therapeutic strategies for the prevention and treatment of chronic allograft rejection	p. 125
Tolerance induction	p. 149
Gene therapy approaches to immunosuppression	p. 169
A rigorous approach to the diagnosis of synergy among combination therapies of immunosuppressive agents	p. 183
Lessons for transplantation of cyclosporine experience in the treatment of autoimmune diseases	p. 201
Subject index	p. 215
Table of Contents provided by Blackwell. All Rights Reserved.

Modern Immunosuppressives

At a Glance

Hardcover

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How to return your order

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