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Methodology for Genetic Studies of Twins and Families : Nato Science Series D: - Michael C. Neale

Methodology for Genetic Studies of Twins and Families

Nato Science Series D:

Hardcover Published: 31st July 1992
ISBN: 9780792318743
Number Of Pages: 496

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Few would dispute the truth of the statement "People are different" but there is much controversy over "why". This book explains the methods used to understand human variation, and extends them far beyond the primary "nature or nurture" question. After chapters on basic statistics, biometrical genetics, matrix algebra and path analysis, there is a state-of-the-art account of how to fit genetic models using the LISREL package. The authors explain not only the assumptions of the twin methods, but how to test them. The elementary model is expanded to cover sex limitation, sibling interaction, multivariate and longitudinal data, observer ratings and twin-family studies. Throughout, the methods are illustrated by applications to diverse areas such as obesity, major depression, alcohol consumptionm delinquency, allergies and common fears.

List of Figures
List of Tables
Contributing Authors
The Scope of Genetic Analysesp. 1
Data Summaryp. 35
Biometrical Geneticsp. 55
Matrix Algebrap. 71
Path Analysis and Structural Equationsp. 87
LISREL Models and Methodsp. 109
Model Fitting Functions and Optimizationp. 131
Univariate Analysisp. 149
Power and Sample Sizep. 189
Social Interactionp. 199
Sex-limitation and G x E Interactionp. 211
Multivariate Analysisp. 231
Direction of Causationp. 261
Repeated Measuresp. 289
Longitudinal Mean Trendsp. 305
Observer Ratingsp. 313
Assortment and Cultural Transmissionp. 329
Future Directionsp. 353
App. A List of Participantsp. 373
App. B The Greek Alphabetp. 381
App. C LISREL Scripts for Univariate Modelsp. 383
App. D LISREL Script for Power Calculationp. 397
App. E LISREL Scripts for Multivariate Modelsp. 399
App. F LISREL Script for Sibling Interaction Modelp. 413
App. G LISREL Scripts for Sex and G x E Interactionp. 415
App. H LISREL Script for Rater Bias Modelp. 437
App. I LISREL Scripts for Direction of Causationp. 445
App. J LISREL Script and Data for Simplex Modelp. 453
App. K LISREL Scripts for Assortment Modelsp. 459
Bibliographyp. 463
Indexp. 485
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9780792318743
ISBN-10: 0792318749
Series: Nato Science Series D:
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 496
Published: 31st July 1992
Publisher: Springer
Country of Publication: NL
Dimensions (cm): 29.7 x 21.0  x 3.38
Weight (kg): 2.01