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Metalloproteinases As Targets for Anti-Inflammatory Drugs : Progress in Inflammation Research - Kevin M.K. Bottomley

Metalloproteinases As Targets for Anti-Inflammatory Drugs

Progress in Inflammation Research

By: Kevin M.K. Bottomley (Editor), David Bradshaw (Editor), John S. Nixon (Editor)

Hardcover Published: October 1999
ISBN: 9783764358563
Number Of Pages: 207

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This volume describes recent research in the field of metalloproteinases (a family of enzymes that can catalyze tissue degradation), in particular their participation in autoimmune diseases such as rheumatoid arthritis, reviewing the latest developments in metalloproteinase inhibitor design and the current status of clinical candidates. This volume is intended not only for those active in research into metalloproteinases but also for those with an interest in inflammatory diseases. Thus it addresses both academic and industrial researchers.

List of contributors
Preface
Structural characteristics of the matrix metalloproteinasesp. 1
Matrix metalloproteinase inhibitorsp. 17
Role of stromelysin-1 in cartilage metabolismp. 59
Matrix metalloproteinases in neuro-inflammatory diseasep. 85
Membrane type matrix metalloproteinases: Regulators of focal proteolysisp. 99
Aggrecanase and cartilage proteoglycan degradationp. 117
Overview of the biological roles of metalloproteinases in health and diseasep. 145
Adhesion molecule sheddasesp. 163
TNF[alpha] converting enzymep. 187
Indexp. 205
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9783764358563
ISBN-10: 3764358564
Series: Progress in Inflammation Research
Audience: General
Format: Hardcover
Language: English
Number Of Pages: 207
Published: October 1999
Publisher: Birkhauser Verlag AG
Country of Publication: CH
Dimensions (cm): 23.39 x 15.6  x 1.42
Weight (kg): 0.49

Earn 678 Qantas Points
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