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The past five years have seen a major leap forward in our understanding of the way proteins fold into their three-dimensional, functional conformations. The rapidly expanding literature covers in vivo as well as in vitro studies and forms the basis for an important biotechnology industry. In this volume, a group of leading scientists review and assess the experimental evidence that underpins these advances and look for signs of a general picture of how proteins fold. Contributors show how such conformational changes are leading to new insights into membrane translocation, pore formation, and the clinically important aggregation phenomena. Students and researchers of biochemistry and molecular biology will find this book to be the ideal introduction to an exciting field.
`The different view and experimental approaches in the chapters should stimulate the protein chemist to search for new ideas and experiments for elucidating the folding phenomenon and approaching to optimale folding models.' D.K. Schwenke, Nahrung 40 (1996)
Series: Frontiers in Molecular Biology
Number Of Pages: 284
Published: 7th April 1994
Country of Publication: GB
Dimensions (cm): 24.6 x 18.8 x 1.7
Weight (kg): 0.56