Mechanics and Energetics of the Myocardium

By: Christian J.F. Holubarsch

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Hardcover | 1 December 2009

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Hardcover
232 Pages

Dimensions(cm)
23.5 x 15.88 x 1.91

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During several decades of this century, the classical physiological studies on the cardiovascular system have greatly improved our knowledge on the function of this system under normal and pathological conditions. This knowledge was the basis of the breakthrough for diagnostic techniques like the Swan-Ganz catheter, coronary arteriography, left and right heart biopsies, and invasive measurements of contractility, as well as therapeutic tools including aortocoronary bypass surgery, percutanous transluminal coronary angioplasty, and a broad field of pharmacological interventions for the whole spectrum of cardiovascular diseases, especially chronic heart failure.
It was during the last decade that the scientific world focused on the evolution of molecular biology of the cardiovascular system so that cardiovascular physiology seemed to become less important. Regarding the myocardium, molecular alterations of important functional proteins (phenotype changes), as well as signal transduction pathways of contractility and cardiac growth have been elucidated. The functional importance of a number of genes has undoubtedly been proven with the help of transgenic animals.
Mechanics and Energetics of the Myocardium provides an overview for those researchers and practioners interested in the broad field of molecular biology and physiology of the cardiovascular system.

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Non-Fiction Medicine Clinical & Internal Medicine Cardiovascular Medicine Pre-Clinical Medicine & Basic Sciences Physiology Other Branches of Medicine Pathology

Preface
Historical Aspects: The Frank-Starling Mechanism	p. 1
The Myothermal Method: Historical and Personal Aspects	p. 17
Papillary Muscle Experiments	p. 23
The Myothermal Approach	p. 47
Skinned Cardiac Fibres	p. 71
The Frequency Response Method	p. 117
Single Cell Experiments	p. 131
Diastolic Compliance	p. 169
The E[subscript MAX] and the PVA Concept	p. 185
Oxygen Consumption Measurements of the Myocardium in the Human Being	p. 195
Table of Contents provided by Blackwell. All Rights Reserved.

Mechanics and Energetics of the Myocardium

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Hardcover

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