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Maternal Substance Abuse and the Developing Nervous System - Ian S. Zagon

Maternal Substance Abuse and the Developing Nervous System

By: Ian S. Zagon (Editor), Theodore A. Slotkin (Editor)

Hardcover

Published: 1st January 1992
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The purpose of this book is to review the basic science and clinical findings concerning maternal substance abuse and the developing nervous system of unborn children. The short-term but vitally significant repercussions of such exposure on biological development, with particular reference to the nervous system, are discussed. The book also discusses the profound influence of maternal substance abuse on behavior in adulthood, which is caused by subtle changes in the chemistry or structure of the developing nervous system. The subject will not only be of interest to clinical and basic science researchers and teachers in the field of maternal substance abuse, but also to individuals in psychology, social work, cellular and molecular biolgoy, embryology, neuroscience, pharmacology, and in clinical professions such as pediatrics, neonatology, and obstetrics. The breadth of topics covered includes alcohol, cocaine, opiates, nicotine, benzodiazepines, marijuana, and the role of stress and hormones. Emphasis is placed on the relationship of the effects of substance abuse on neurotrophic factors and receptors.
Key Features
* Shows how abused substances act directly or indirectly to mimic or influence the action of neurotrophic factors
* Explains that the transient expression of peptides, neurotransmitters, and receptors can be markedly disturbed by drugs
* Demonstrates that animal and tissue culture studies are consistent with clinical observations and important in understanding and ameliorating adverse actions of drugs in early life

Introduction
Fetal Alcohol Syndrome and Fetal Alcohol Effects: Later Developmental Consequences: A Clinical Perspective
The Effects of Prenatal Alcohol Exposure
Fetal Alcohol Effects: Recent Laboratory Findings Using a Rat Model of Alcohol Exposure during the Brain Growth Spurt
Smoking: Clinical Implications Cause and Effect: Toward Determining Long-Term Teratogenicity
Prenatal Exposure to Nicotine: What Can We Learn from Animal Models?
Prenatal Cocaine and Marijuana Exposure: Research and Clinical Implications
Cocaine and the Developing Nervous System: Laboratory Findings
Maternal Opioid Drug Use and Child Development
Effects of Opiates on the Physiology of the Fetal Nervous System
Maternal Exposure to Opioids and the Developing Nervous System: Laboratory Findings
Benzodiazepines and the Developing Nervous System: Laboratory Findings and Clinical Implications
The Analysis of Drug Effects Upon Sexual Differentiation of the Brain: The Role of Stress and Hormones in Drug Actions
Chapter References
Index
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780127752259
ISBN-10: 0127752250
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 377
Published: 1st January 1992
Publisher: ACADEMIC PR INC
Country of Publication: US
Dimensions (cm): 23.62 x 15.77  x 2.24
Weight (kg): 0.68