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Leukemia : Advances in Research and Treatment :  Advances in Research and Treatment - Emil J. Freireich

Leukemia : Advances in Research and Treatment

Advances in Research and Treatment

By: Emil J. Freireich (Editor), Hagop Kantarjian (Editor)

Hardcover

Published: March 1993
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Leukemia continues to offer the scientist a unique opportunity to gain new knowledge about the malignant transformation. As a result, this multi-authored volume, devoted to advances which have occurred over the last seven years, provides the reader with an important new understanding of leukemia, but perhaps even more important, predicts analogous, new developments in the other malignant diagnoses. In this respect, this volume represents the cutting edge of cancer research. This text is unique in that it includes in a single volume the leading contributors to their respective fields covering what the editors feel are the major advances in our knowledge of the biology and therapy of leukemia over the last seven years.

List of Contributors
Preface
All trans retinoic acid as a targeting drug for differentiation therapy in acute promyelocytic leukemiap. 1
Hairy cell leukemia: New understanding of biology and treatmentp. 15
Uses of polymerase chain reaction in leukemia: Detection of minimal residual disease and identification of novel genetic mutationsp. 35
The cell surface receptor encoded by the proto-oncogene KIT and its ligandp. 45
Human T-cell lymphoma/leukemia retroviruses and malignancyp. 79
Fludarabine phosphate in the treatment of chronic lymphocytic leukemia: Biology, clinical impact, and future directionsp. 105
The role of immunotherapy in the treatment of acute myeloblastic leukemia: From allogeneic bone marrow transplantation to the application of interleukin 2p. 121
Detection of minimal residual disease in ALLp. 135
Cytokines and myeloid-specific genes: Patterns of expression and possible role in proliferation and differentiation of acute myelogenous leukemia cellsp. 171
The immunological treatment of human marrow in vitro in transplant biologyp. 189
Monoclonal antibodies in the treatment of myelogenous leukemiasp. 213
Prognosis and therapy of myelodysplastic syndromesp. 233
Multidrug resistance in leukemiap. 269
The molecular pathogenesis of the Philadelphia-positive leukemias: Implications for diagnosis and therapyp. 295
Indexp. 327
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9780792319672
ISBN-10: 0792319672
Series: Cancer Treatment and Research
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 336
Published: March 1993
Publisher: Springer
Country of Publication: NL
Dimensions (cm): 23.5 x 15.5  x 2.0
Weight (kg): 0.68