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Lacrimal Gland, Tear Film and Dry Eye Syndromes Vol. 1 : Basic Science and Clinical Relevance :  Basic Science and Clinical Relevance - B. Britt Bromberg

Lacrimal Gland, Tear Film and Dry Eye Syndromes Vol. 1 : Basic Science and Clinical Relevance

Basic Science and Clinical Relevance

By: B. Britt Bromberg (Adapted By), Darlene A. Dartt (Adapted By), David A. Sullivan (Editor), Donald L. Mackeen (Adapted By), Michelle M. Cripps (Adapted By)

Hardcover

Published: 1994
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Proceedings of the International Conference on [title], held in Southampton, Bermuda, November 1992. Following the keynote address (Regulation of Tear Secretion by D.A. Dartt), the volume covers: lacrimal gland anatomy and innervation/ electrophysiology, water and ion transport/signal transduction

Regulation of Tear Secretionp. 1
The Anatomy and Innervation of Lacrimal Glandsp. 11
Light and Electron Microscopic Morphology of Accessory Lacrimal Glandsp. 19
Immunohistochemistry and Protein Secretion in the Rat Lacrimal Gland: A Morphophysiological Studyp. 25
Carbonic Anhydrase and Acinar Cell Heterogeneity in Rat and Rabbit Lacrimal Glandsp. 31
Basement Membrane Modulation of Stimulated Secretion by Lacrimal Acinar Cellsp. 37
Galactose-Binding Sites in the Acinar Cells of the Human Accessory Lacrimal Glandp. 45
Thoughts on the Ductules of the Aging Human Lacrimal Glandp. 49
The Parenchyma Accompanying Major Extraglandular Ducts within the Rat Lacrimal Cordp. 53
Protein Secretion and the Identification of Neurotransmitters in the Isolated Pig Lacrimal Glandp. 57
Anti-Muscarinic Acetylcholine Receptor-Like Immunoreactivity in Lacrimal Glandsp. 61
Innervation and Mast Cells of the Rat Lacrimal Gland: The Effects of Agep. 67
Immunogold Localization of Prolactin in Acinar Cells of Lacrimal Glandp. 75
Subcellular Organization of Ion Transporters in Lacrimal Acinar Cells: Secretagogue-Induced Dynamicsp. 79
Effect of Acetylcholine on the Membrane Conductance of the Intralobular Duct Cells of the Rat Exorbital Lacrimal Glandp. 87
The Circadian Rhythm of Lacrimal Secretion and Its Parameters, Determined in a Group of Healthy Individuals, and Its Potential Diagnostic and Therapeutic Significancep. 93
Effects of Dihydrotestosterone and Prolactin on Lacrimal Gland Functionp. 99
A Na:H Exchanger Subtype Mediates Volume Regulation in Bovine Corneal Epithelial Cellsp. 105
Endocytosis and Exocytosis in Rabbit Lacrimal Gland Acinar Cellsp. 111
The Inositol Phosphate-Calcium Signalling System in Lacrimal Gland Cellsp. 115
Characterization of Rat Lacrimal Gland Protein Kinase C: Effects of Phorbol Esters and PKC Inhibitors on Histone Kinase Activity and Labelled Protein Dischargep. 121
Inhibition of Lacrimal Function by Selective Opiate Agonistsp. 127
Second Messenger Modulation of IgG Secretion from Chicken Lacrimal Glandp. 133
Identification of Sigma Receptors in Lacrimocytes and Their Therapeutic Implication in Dry Eye Syndromep. 141
Role of Protein Kinase C in [alpha][subscript 1]-Adrenergic and Cholinergic Agonist Stimulated Protein Secretionp. 147
The Role of Membrane Channels in IgG Secretion by Plasma Cells in the Chicken Lacrimal Glandp. 151
Binding Characteristics, Immunocytochemical Location and Hormonal Regulation of Androgen Receptors in Lacrimal Tissuep. 157
Regulation of Lacrimal Gland Immune Responsesp. 161
The Lacrimal Antibody Response to Viral and Chlamydial Infectionsp. 169
Neural-Endocrine Control of Secretory Component Synthesis by Lacrimal Gland Acinar Cells: Specificity, Temporal Characteristics and Molecular Basisp. 175
Lymphocyte Adhesive Interaction with Lacrimal Gland Acinar Epithelium Involves Carbohydrate Recognitionp. 181
Subclass Expression of IgA in Lacrimal Glands of Patients with Sjogren's Syndromep. 185
Influence of the Endocrine Environment on Herpes Virus Infection in Rat Lacrimal Gland Acinar Cellsp. 189
Sialodacryoadenitis Virus Infection of Rat Lacrimal Gland Acinar Cellsp. 193
Growth Factor and Receptor Messenger RNA Production in Human Lacrimal Gland Tissuep. 197
Human Lacrimal Gland Secretes Proteins Belonging to the Group of Hydrophobic Molecule Transportersp. 205
Transcription of Message for Tumor Necrosis Factor-Alpha by Lacrimal Gland is Regulated by Corneal Woundingp. 211
Androgen Regulation of Secretory Component mRNA Levels in the Rat Lacrimal Glandp. 219
Vasoactive Intestinal Peptide Induces Primary Response Gene Expression in Lacrimal Glandp. 225
Composition and Biophysical Properties of the Tear Film: Knowledge and Uncertaintyp. 231
Structure and Function of the Tear Filmp. 239
Ocular Surface Changes Induced by Repeated Impression Cytologyp. 249
Developmental Appearance of a Component of the Glycocalyx of the Ocular Surface Epithelium in the Ratp. 255
Mixing of the Tear Film under the Eyelidsp. 263
Viscoelastic Properties of Human Tears and Polymer Solutionsp. 267
Effect of Age on Human Tear Film Evaporation in Normalsp. 271
Advances in Ocular Tribologyp. 275
Effect of Systemic Ingestion of Vitamin and Trace Element Dietary Supplements on the Stability of the Pre-Corneal Tear Film in Normal Subjectsp. 285
Patterns of Cytokeratin Expression in Impression Cytology Specimens from Normal Human Conjunctival Epitheliump. 289
Increase in Tear Film Lipid Layer Thickness Following Treatment of Meibomian Gland Dysfunctionp. 293
Analysis and Function of the Human Tear Proteinsp. 299
Tear Protein Composition and the Effects of Stimulusp. 309
Growth Factors in Human Tear Fluid and in Lacrimal Glandsp. 315
Re-Examination of the Origin of Human Tear LDHp. 321
Tear Proteins and Enzymes in the Chimpanzeep. 327
Comparisons of Tear Proteins in the Cow, Horse, Dog and Rabbitp. 331
Tear Protein G Originates from Denatured Tear Specific Prealbumin as Revealed by Anti-TSP Antibodyp. 335
Tear Lactoferrin Levels and Ocular Bacterial Flora in HIV Positive Patientsp. 339
Vitronectin in Human Tears - Protection Against Closed Eye Induced Inflammatory Damagep. 345
Mucopolysaccharide Degrading Enzymes (MPDE) in the Tear Fluid: A New Diagnostic Test for Rapid Detection of Acute Ocular Infectionsp. 351
Tear Immunoglobulins and Lysozyme Levels in Corneal Ulcersp. 355
Mucus and Pseudomonas aeruginosa Adherence to the Corneap. 359
Measurement of Human Tear Lysozyme Using a Novel Synthetic Substratep. 363
Retrospective Use of Frozen Schirmer Strips for the Measurement of Tear Lysozymep. 367
Rapid Measurement of Selected Tear Proteins in Health and Disease Using the Touch Tear Microassay Systemp. 371
The Tear Film: Pharmacological Approaches and Effectsp. 377
Influence of Various Pharmaceutical Agents on Tear Flow as Assessed by Fluorophotometryp. 385
Neural Stimulation of Conjunctival Goblet Cell Mucous Secretion in Ratsp. 393
Bioavailability of Prednisolone in Rabbits: Comparison of a High-Viscosity Gel and an Aqueous Suspension - Single- and Repeated Applicationsp. 399
Tear Film - Contact Lens Interactionp. 403
Electrophoretic Patterns of Human Denatured Tear Proteins and Glycoproteins from Normal Subjects and Soft Contact Lens Wearersp. 411
The Refractive Index of Tears in Normals and Soft Lens Wearersp. 417
The Role of Tear Deposits on Hydrogel Contact Lenses Induced Bacterial Keratitis: Pseudomonas aeruginosa Abhesivesp. 421
The Closed-Eye Challengep. 427
Dry Eye Therapy: Evaluation of Current Directions and Clinical Trialsp. 431
Artificial Tear Issuesp. 437
Evaluation of Effects of a Physiologic Artificial Tear on the Corneal Epithelial Barrier: Electrical Resistance and Carboxyfluorescein Permeabilityp. 441
Evaluation of a Physiological Tear Substitute in Patients with Keratoconjunctivitis Siccap. 453
A Scanning Electron Micrographic Comparison of the Effects of Two Preservative-Free Artificial Tear Solutions on the Corneal Epithelium as Compared to a Phosphate Buffered Saline and a 0.02% Benzalkonium Chloride Controlp. 459
A Unique Therapeutic Artificial Tear Formulationp. 465
Non-Sjogren Dry Eye: Pathogenesis, Diagnosis and Animal Modelsp. 471
Abnormalities of the Structure of the Superficial Lipid Layer on the In Vivo Dry-Eye Tear Filmp. 489
Tear Osmolarity - a New Gold Standard?p. 495
Micropachometric Differentiation of Dry Eye Syndromesp. 505
Decreased Tear Secretion in Chernobyl Children: External Eye Disorders in Children Subjected to Long-Term Low-Dose Radiationp. 513
Lacrimal Dysfunction in Pediatric Acquired Immunodeficiency Syndromep. 517
Keratoconjunctivitis Sicca in HIV-1 Infected Female Patientsp. 521
The Increase of the Blink Interval in Ophthalmic Proceduresp. 525
Changes in Tear Ion Concentrations in Dry-Eye Disordersp. 529
Quantitative Cellular Evaluation of Conjunctival Squamous Metaplasia in the Dry Eye Patientp. 535
Topical Anesthetic Induced Pain as a Diagnostic Tool for Keratoconjunctivitis Sicca (KCS)p. 539
Lacrimation Kinetics as Determined by a Schirmer-Type Techniquep. 543
A Precise Method of Using Rose Bengal in the Evaluation of Dry Eye and the Detection of Changes in Its Severityp. 549
Dry Eye Syndromes: Treatment and Clinical Trialsp. 553
Keratoprosthesis in End-Stage Dry Eyep. 561
Amylase in Mare Lacrimale in Patients with Submandibular Salivary Gland Transplantation to the Lacrimal Basinp. 565
A Subjective Approach to the Treatment of Dry Eye Syndromep. 571
Simulation of Lacrimal Gland Output: a Tear Jet for Replacing Eye Moisture in Sjogren's Syndromep. 577
Characteristics of a Canine Model of KCS: Effective Treatment with Topical Cyclosporinep. 583
Treatment of Severe Eye Dryness and Problematic Eye Lesions with Enriched Bovine Colostrum Lactoserump. 595
The Efficiency of Short-Wave Diathermy and Laser Stimulation of the Lacrimal Gland in the Treatment of Dry Eye Syndromep. 601
Effect of Collagen Punctal Occlusion on Tear Stability and Volumep. 605
Sjogren's Syndrome: Immunologic and Neuroendocrine Mechanismsp. 609
Murine Models of Sjogren's Syndromep. 623
Utilization of the Non-Obese Diabetic (NOD) Mouse as an Animal Model for the Study of Secondary Sjogren's Syndromep. 631
Expression of Granzyme A and Perforin in Lacrimal Gland of Sjogren's Syndromep. 637
Epstein-Barr Virus and the Lacrimal Gland Pathology of Sjogren's Syndromep. 641
Sjogren's Syndrome (SS) and Epstein-Barr Virus (EBV) Reactivationp. 647
Hypothesis for Autoantigen Presentation and T Cell Activationp. 651
Gingival Impression: A New Biological Test for Xerostomia in Diagnosis of Sjogren's Syndromep. 655
Sjogren's Syndrome Diagnosis: A Comparison of Conjunctival and Gingival Impressions and Salivary Gland Biopsyp. 661
Correlation of Labial Salivary Gland Biopsies with Ocular and Oral Findings in Patients with Sjogren's Syndromep. 667
A Comparative Study Between Tear Protein Electrophoresis and Accessory Salivary Gland Biopsy in Sjogren's Syndromep. 671
Sjogren's Syndrome - Close to Cause and Cure?p. 679
Androgen-induced suppression of autoimmune disease in lacrimal glands of mouse models of Sjogren's syndromep. 683
Effect of Sodium Sucrose-Sulfate on the Ocular Surface of Patients with Keratoconjunctivitis Sicca in Sjogren's Syndromep. 691
Comparative Efficacy of Androgen Analogues in Suppressing Lacrimal Gland Inflammation in a Mouse Model (MRL/lpr) of Sjogren's Syndromep. 697
National Sjogren's Syndrome Associationp. 701
Sjogren's Syndrome Foundation Inc.p. 705
Advertisement: Lacrimedics, Inc.p. 709
Contributorsp. 711
Indexp. 715
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9780306446764
ISBN-10: 0306446766
Series: Lacrimal Gland, Tear Film, & Dry Eye Syndromes
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 729
Published: 1994
Publisher: SPRINGER VERLAG GMBH
Country of Publication: US
Dimensions (cm): 23.37 x 16.26  x 4.57
Weight (kg): 1.16