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Laboratory Techniques in Thrombosis : A Manual :  A Manual - J. Jespersen

Laboratory Techniques in Thrombosis : A Manual

A Manual

By: J. Jespersen (Editor), R. M. Bertina (Editor), F. Haverkate (Editor)

Hardcover Published: December 1998
ISBN: 9780792353171
Number Of Pages: 308

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The first edition of this manual appeared in 1992 and was entitled ECAT Assay Procedures . This completely revised new edition combines the strengths of the first edition with new and useful features. Laboratory Techniques in Thrombosis - a Manual still gives detailed descriptions of the recommended assays and their alternatives. However, the manual now has a broader scope because it is no longer limited by the frontiers of ECAT. Experts all over the world have contributed to this edition. Furthermore, new assays have been introduced, improvements have been suggested for other assays, while a few others have become redundant or no longer available. The list of manufacturers is fully updated and a list of the recommended nomenclature of quantities in thrombosis and haemostasis is new to this edition, further facilitating the use of this manual. Laboratory Techniques in Thrombosis - a Manual will contribute to furthering the much needed harmonization and standardization of tests within the field and should have a place in all working haemostasis laboratories.

`The objective towards standardization is largely met, since world experts on each assay collaborated to evaluate and compare the available methodologies and point to the advantages and disadvantages of each one. This book is written for clinical thrombosis and hemostasis laboratorians. Another attractive feature is the degree of expertise recruited to produce these critical summaries of existing methodologies. This book is a long overdue update of the first edition in view of the multitude of newly developed methodologies and the number of manufacturers involved.' Demetra D. Callas, Loyola University Medical Center in Doody Publishing Inc.

Preface to the Second Editionp. ix
Preface to the First Editionp. xi
List of Contributorsp. xiii
Nomenclature of haemostasis factorsp. xvii
Introduction to laboratory assays in haemostasis and thrombosisp. 1
Good medical laboratory services - guidelinesp. 9
Blood collection and sample preparation: pre-analytical variationp. 21
Quality assessment of haemostatic assays and external quality assessment schemesp. 29
Activated partial thromboplastin time (APTT)p. 37
Prothrombin time (PT)p. 45
Endogenous thrombin potentialp. 63
Fibrinogenp. 79
Activated factor VIIp. 89
Factor VII activity and antigenp. 99
Factor VIII clotting activityp. 107
Von Willebrand factorp. 115
Antithrombin activity and antigenp. 121
Protein C activity and antigenp. 129
Protein S antigenp. 141
Protein S activityp. 153
Activated protein C (APC) resistancep. 163
Tissue factor pathway inhibitor (TFPI)p. 171
Lupus anticoagulantp. 183
Heparin cofactor IIp. 189
Fibrinopeptide A (FPA)p. 199
Thrombin-antithrombin (TAT) complexesp. 209
Prothrombin fragment F1+2p. 217
Tissue-type plasminogen activator (t-PA) activityp. 223
Tissue-type plasminogen activator antigen (t-PA Ag)p. 231
Plasminogen activator inhibitor-1 (PAI-1) antigenp. 239
Plasminogen activityp. 247
Plasmin inhibitor activity (previously [alpha][subscript 2]-antiplasmin)p. 257
Plasmin-[alpha][subscript 2]-antiplasmin complexes (plasmin-plasmin inhibitor complexes)p. 265
Soluble fibrin and degradation products of fibrinogen (FgDP), fibrin (FbDP; D-dimer) and total of FgDP and FbDP (TDP)p. 275
Venous occlusion test in fibrinolysis assaysp. 285
List of manufacturersp. 293
Indexp. 305
Table of Contents provided by Syndetics. All Rights Reserved.

ISBN: 9780792353171
ISBN-10: 079235317X
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 308
Published: December 1998
Publisher: Springer
Country of Publication: NL
Dimensions (cm): 23.5 x 15.5  x 1.91
Weight (kg): 1.41
Edition Number: 2
Edition Type: Revised