Introduction to Cell Mechanics and Mechanobiology

By: Christopher R. Jacobs, Hayden Huang, Mohammad R. Kaazempur Mofrad

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eText | 24 September 2026 | Edition Number 2

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Published: 16th November 2012

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This comprehensive second edition provides a pedagogical introduction to cell mechanics and mechanobiology. featuring quantitative descriptions of key concepts and solved examples throughout. The textbook demonstrates how understanding cellular responses to mechanical forces allows us to predict cell behavior and functionality in various environments.

Introduction to Cell Mechanics and Mechanobiology, Second Edition, asks key questions about the quantitative concepts that comprise this interdisciplinary field. The authors provide clear explanations of complex mechanobiological phenomena, from single-molecule mechanics to whole-cell responses. This book covers essential topics, including cellular polymers, cytoskeleton networks, membrane mechanics, and mechanotransduction. There are primer chapters on solid mechanics, fluid mechanics, statistical mechanics, and cell biology to ensure accessibility for students from diverse backgrounds.

Designed for advanced undergraduate and graduate students in biomedical engineering, bioengineering, and mechanical engineering, users will appreciate complete derivations of relevant equations, practical laboratory applications, and comprehensive coverage of nuclear biomechanics. The twelve detailed chapters provide a complete framework for understanding the technical and biological aspects of cellular mechanics. Thus, this book is an invaluable resource for mastering the quantitative principles of mechanobiology.