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Inflammatory Bowel Diseases : From Bench to Bedside : Falk Symposium - T. Andus

Inflammatory Bowel Diseases : From Bench to Bedside

Falk Symposium

By: T. Andus (Editor)

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Several international symposia on chronic inflammatory bowel disease over the last few years have contributed to our understanding of the pathophysiology and treatment of this condition. Molecular biology and new analytical techniques have continuously improved our knowledge of mucosal immunology and of inflammatory reactions. Progress in this field is very rapid and has implications for diagnosis and treatment, and makes it important to have a scientific exchange between basic research and clinical practice. This volume, the proceedings of Falk Symposium No. 96, held in Freiburg, Germany, October 30- November 1, 1996, documents the transfer of knowledge between clinicians and basic scientists, and clarifies the definitions used in daily practice such as active disease, refractory diseases or remission. The book will open new aspects for future research and clinical work in the field of inflammatory bowel diseases.

List of Principal Contributors
Preface
The genetics of inflammatory bowel disease: new datap. 5
Current and future parameters for stratification of inflammatory bowel diseases: clinical phenotypes, subclinical markers, cytokine-specific inflammatory patterns, and therapeutic responsesp. 13
Genetic and chemical models of inflammatory bowel diseasep. 21
Inflammatory bowel disease: an alternative hypothesisp. 27
Epidemiologyp. 39
Nutrition - are there new facts? The importance of n-3 polyunsaturated fatty acids and long chain triglyceride in the treatment of inflammatory bowel diseasep. 44
Smoking and oral contraceptives in inflammatory bowel diseasep. 62
The role of microbial flora in chronic intestinal inflammation: recent developmentsp. 69
Inflammatory bowel disease: microvascular pathogenesis and persistent measles virus infectionp. 79
Intestinal macrophages in inflammatory bowel diseasep. 93
The role of lymphocytes in the pathogenesis of inflammatory bowel diseasep. 97
Epithelial cells in inflammatory bowel diseasep. 103
Biology of mature human intestinal mast cellsp. 117
Are there other important cells? Characterization of intestinal fibroblasts in Crohn's diseasep. 126
Prostaglandins, leukotrienes, platelet activating factor and nitric oxidep. 133
Regulation of chronic gut inflammation by reactive oxygen metabolitesp. 139
Neuropeptides in inflammatory bowel diseasep. 145
Collagen metabolism in inflammatory bowel diseasep. 157
Neuro-immune interactions in inflammatory bowel diseasep. 167
Tumour necrosis factor and its receptorsp. 175
Growth factorsp. 184
Are adhesion molecules important in inflammatory bowel disease?p. 193
Inflammatory bowel disease: what are we looking for?p. 211
Treatment decisions in inflammatory bowel disease based on endoscopyp. 223
When to use radiology and when scintigraphyp. 228
Laboratory test in inflammatory bowel diseasep. 235
Backwash ileitis in ulcerative colitis - new aspects in the assessment of the diseasep. 245
Ultrasoundp. 250
Inflammatory bowel disease and the kidneyp. 255
Morphological and functional defects of the brain in inflammatory bowel diseasep. 263
Sulphasalazine and alternative aminosalicylates: how much is necessary?p. 271
Old and new steroids for the treatment of inflammatory bowel diseasep. 277
Immunosuppressants: which and when? Randomized controlled trials provide some answersp. 288
The role of antibiotics in Crohn's disease treatmentp. 305
Nutrition in inflammatory bowel diseasep. 311
IL-10 induces long-term antigen-specific T-cell tolerance: consequences for inflammatory bowel diseasep. 323
Modulation of cytokines for experimental treatment of chronic intestinal inflammationp. 331
Immune modulation of Crohn's disease - clinical studiesp. 337
Prevention of intestinal strictures by polyunsaturated phosphatidylcholinesp. 342
Proctocolectomy for ulcerative colitis: when, how, and what are the results?p. 349
The optimal approach to a patient with refractory Crohn's diseasep. 363
Anal fistulae in Crohn's disease - when and how to treat?p. 367
Prevention of postoperative recurrence in Crohn's diseasep. 372
Monitoring of recurrence after surgery for Crohn's diseasep. 378
The steroid-dependent patientp. 387
Dysplasiap. 397
Osteopeniap. 402
Anaemiap. 407
Short bowel syndromep. 411
Medical treatment of pouchitis following ileal pouch-anal anastomosis for ulcerative colitisp. 421
Present and future treatments: facts, hopes, and fantasiesp. 435
Indexp. 443
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9780792387282
ISBN-10: 0792387287
Series: Falk Symposium
Audience: Professional
Format: Hardcover
Language: English
Number Of Pages: 480
Country of Publication: NL
Dimensions (cm): 24.0 x 16.0
Weight (kg): 0.95