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Hydroxy-Pyridones as Antifungal Agents with Special Emphasis on Onychomycosis - Sam Shuster

Hydroxy-Pyridones as Antifungal Agents with Special Emphasis on Onychomycosis

By: Sam Shuster (Editor)

Paperback ISBN: 9783540654940
Number Of Pages: 109

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This text summarizes the results of two symposia held on hydroxy pyridones as antifungal agents and organized on the occasion of the International Summit on Cutaneous Antifungal Therapy 1996 in Vancouver and the 19th World Congress of Dermatology 1997 in Sydney. Some of the papers deal with the basic mechanisms of action and how these translate into product features, for example activity spectrum. Other papers describe the unique properties of hydroxy pyridones, such as high penetration into and through keratinic tissues or their activity as dual inhibitor on 5 lipoxygenase and cyclooxygenase which leads to an anti-inflammatory effect. Last but not least, various accounts are given which show how this unique product profile aids the treatment of various fungal diseases, especially onychomycosis.

Hydroxy-Pyridones Outstanding Biological Propertiesp. 1
Enzyme Histochemical Investigations of Candida albicans After Treatment with Rilopirox, a Novel Fungicidal Hydroxy-Pyridonep. 11
Can Ciclopirox Be Used as a Broad-Spectrum Anti-Infective Agent?p. 18
Studies of the Anti-Inflammatory Properties of Ciclopiroxp. 33
Measurement of Ciclopirox Permeation Through Fingernail Models by Novel Spectroscopic Techniquesp. 36
Dermatomycosis: A Multifactorial Diseasep. 39
Efficacy of Topical Batrafenp. 43
Ciclopirox Gel Treatment of Scalp Seborrhoeic Dermatitisp. 45
Seborrhoeic Dermatitis and Dandruff, and Its Treatment With Ciclopirox Shampoop. 51
Epidemiology of Mycological Infections in Children - in South Americap. 56
Clinical Efficacy of Topical Ciclopirox Nail Lacquer: Double-Blind United States Studies on Onychomycosisp. 62
Dose Regimen Studies with Ciclopirox Nail Lacquerp. 69
Open Studies of Ciclopirox Nail Lacquer in Onychomycosis - A Reviewp. 75
Influence of Onychomycosis on the Quality of Lifep. 81
Treatment of Onychomycosis: Pharmacoeconomic Aspectsp. 91
The Safety Aspects of Systemic and Topical Antifungal Agents Used in the Management of Onychomycosisp. 96
Differential Diagnosis of Onychomycosis and Rationale for a Step-Therapy in Treating Nail Fungal Infectionp. 103
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9783540654940
ISBN-10: 3540654941
Audience: General
Format: Paperback
Language: English
Number Of Pages: 109
Publisher: Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
Country of Publication: DE
Dimensions (cm): 23.39 x 15.6  x 0.64
Weight (kg): 0.18