Cervical cancer is a major disease worldwide, with 500,000 new cases diagnosed every year. Through aetiological studies, an association has been established with HPV infection throughout the pathological spectrum of this disease. A timely review of HPV infection in cervical cancer, this book provides the background to the potential for immunological intervention. Basic background is provided, ensuring the book's accessibility to all. Each
chapter is integrated so that the book as a whole provides a detailed insight into the most relevant scientific issues of HPV and cervical cancer. This book will provide an interface for students,
scientists and clinicians with a realistic and critical evaluation of the advances and problems in the implementation of immunologically based prophylactic and therapeutic strategies in HPV-associated disease.
`this book can be strongly recommended to a wide audience in our field'
Charles Lacey, Papillomavirus Report 6 (1) 1995, Leeds Medical Information
`the field of HPV biology and immunology is covered in a very relevant way in the monograph and the book will be of great use for both students at a graduate level with knowledge in biology and immunology and for scientists updating their knowledge on HPV'
Bodil Norrild, FEBS Letters 367 (1995)
`This book is a timely review of HPV infection in cervical cancer and provides the background to the potential for immunological intervention.'
Anticancer Research 15: (1995)
1: The pathology of cervical intro-epithelial neoplasia carcinoma and human papilloma-virus infection
2: Molecular genetics of human papilloma viruses
3: Detection of human papilloma virus infections
4: Epidemiology of HPV and cervical cancer
5: Mechanisms of transformation by HPV
6: Virus keratinocyte interactions in the infectious cycle
7: Serological immune response to HPV
8: the search for cell-mediated immunity to HPV: prospects for vaccine design
9: MHC expression in the natural history of cervical cancer
10: Towards vaccines against papilloma virus
11: Immunological aspects of cutaneous warts
12: Concluding remarks