Acquired chromosome abnormalities are associated with malignancy, exposure to mutagenic agents, and some chromosome instability syndromes. Their study often entails extensive modification of standard cytogenetic techniques as well as a very different approach to analysis. This is the first comprehensive manual of techniques for the study of acquired chromosome abnormalities, and as such will be an invaluable source of information for cytogeneticists, hematologists, and oncologists. Since the interpretation of chromosome preparations is notoriously difficult in some of these conditions, illustrations, both diagrammatic and photographic, of all chromosome rearrangements discussed are an important feature of this book. In addition to basic techniques, the book takes a futuristic look at new technology which is becoming important in the study of cytogenetics, particularly in the field of cancer research.
B.H. Czepulkowski & B. Bhatt, & D.E. Rooney: Basic techniques for the preparation and analysis of chromosomes from bone marrow and leukaemic blood; A.M. Potter & A. Watmore: Cytogenetics in myeloid leukaemia; B. Gibbons, & B.H. Czepulkowski: Cytogenetics in acute lymphoblastic leukaemia; C.J. Harrison: The lymphomas and chronic lymphoproliferative disorders; B. Bain: The role of cytogenetics in the assessment of haematological
disorders; N. Mandahl: Methods in solid tumour cytogenetics; E.J. Tawn & D. Holdsworth: Mutation-induced chromosome damage in human lymphocytes; R.T. Howell & A.M.R. Taylor: Chromosome instability syndromes; J.K. Cowell: Somatic cell
hybrids in the analysis of the human genome; D.M. Lillington, F.E. Cotter, & P. N. Riddle: Microdissextion of human metaphase chromosomes; Appendix; Index.
Series: Human Cytogenetics: A Practical Approach : Book 2
Number Of Pages: 318
Published: 6th August 1992
Publisher: Oxford University Press
Country of Publication: GB
Dimensions (cm): 23.4 x 15.6
Weight (kg): 0.55
Edition Number: 2
Edition Type: Revised