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How Scientists Explain Disease - Paul Thagard

How Scientists Explain Disease

Paperback Published: 30th July 2000
ISBN: 9780691050836
Number Of Pages: 268

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How do scientists develop new explanations of disease? How do those explanations become accepted as true? And how does medical diagnosis change when physicians are confronted with new scientific evidence? These are some of the questions that Paul Thagard pursues in this pathbreaking book that develops a new, integrative approach to the study of science.

Ranging through the history of medicine, from the Hippocratic theory of humors to modern explanations of Mad Cow Disease and chronic fatigue syndrome, Thagard analyzes the development and acceptance of scientific ideas. At the heart of the book is a case study of the recent dramatic shift in medical understanding of peptic ulcers, most of which are now believed to be caused by infection by the bacterium "Helicobacter pylori." When this explanation was first proposed in 1983, it was greeted with intense skepticism by most medical experts, but it became widely accepted over the next decade. Thagard discusses the psychological processes of discovery and acceptance, the physical processes involving instruments and experiments, and the social processes of collaboration, communication, and consensus that brought about this transformation in medical knowledge.

"How Scientists Explain Disease" challenges both traditional philosophy of science, which has viewed science as largely a matter of logic, and contemporary science studies that view science as largely a matter of power. Drawing on theories of distributed computing and artificial intelligence, Paul Thagard develops new models that make sense of scientific change as a complex system of cognitive, social, and physical interactions.

This is a book that will appeal to all readers with an interest in the development of science and medicine. It combines an engaging style, significant research, and a powerfully original argument.

Industry Reviews

"Thagard ... presents a detailed structure for the scientific understanding of disease... [A] valuable work... Recommended."--Library Journal "This book is remarkable for its clarity and its lack of doctrine. At each stage, Thagard outlines in plain terms precisely what he is trying to explain, and illustrates his explanation ... It is precisely this even-handed and commonsense approach that allows him to give an accurate portrayal of what scientific advance is like. If this is what philosophers can do for science and medicine, we need more help from them."--Charles Bangham, The Times Higher Education Supplement "An engaging look at contemporary medical science."--K. Codell Carter, Journal of the History of Medicine "For anyone who has practised medicine long enough to wonder how and why some theories become fashionable and others fail to thrive, this book will make an interesting read. Paul Thagard finds both the traditional view of science as logic and the postmodern view of science as power inadequate for understanding how science develops."--Julia Lowe, British Medical Journal "This clear and easy to read book is suitable for the general public and students, as well as professional philosophers of science... The general reader will appreciate introductions to the logical, cognitive, and sociological approaches to the study of science... Useful summaries at the end of each chapter allow a quick read of main points."--Lindley Darden, Philosophy of Science

List of Figures
List of Tables
Explanationsp. 1
Explaining Sciencep. 3
Explaining Diseasep. 20
The Bacterial Theory of Peptic Ulcersp. 37
Ulcers and Bacteria: Discoveryp. 39
Ulcers and Bacteria: Acceptancep. 56
Ulcers and Bacteria: Instruments and Experimentsp. 71
Ulcers and Bacteria: Social Interactionsp. 84
Cognitive Processesp. 99
Causes, Correlations, and Mechanismsp. 101
Discovering Causes: Scurvy, Mad Cow Disease, AIDS, and Chronic Fatigue Syndromep. 118
Medical Analogiesp. 135
Diseases, Germs, and Conceptual Changep. 148
Social Processesp. 165
Collaborative Knowledgep. 167
Medical Consensusp. 185
Science and Medicine on the Internetp. 199
Conclusionp. 217
Science as a Complex Systemp. 219
Referencesp. 243
Indexp. 259
Table of Contents provided by Publisher. All Rights Reserved.

ISBN: 9780691050836
ISBN-10: 069105083X
Audience: Tertiary; University or College
Format: Paperback
Language: English
Number Of Pages: 268
Published: 30th July 2000
Country of Publication: US
Dimensions (cm): 23.34 x 15.55  x 1.78
Weight (kg): 0.41