The field of endocrinology has exploded in the last 20 years because of advances in molecular and cell biology. This text integrates new knowledge about hormone structure and function with the more classical focus on endocrine physiology and metabolic disorders. The editors have assembled contributions by some of the world's leading endocrine researchers and clinical scientists. The result is an illustrated text that integrates findings from studies of structure, biosynthesis, genetics, metabolism and pathophysiology. Molecular structures of hormones and receptor families growth factors, and related oncogenes are presented. Fertility control, in vitro fertilization, and aging are discussed, as is the role of hormones in related pathophysiologies such as cancer, diabetes, and growth disorders. This text begins with an illustrated introductory chapter by Professor Baulieu that surveys virtually all areas of the subject, from the molecular aspects of hormonal communication between cells to comparative evolutionary endocrinology. Subsequent chapters concentrate on specific hormone systems.
Following each chapter, molecular biologists, biochemists and endocrinologists contribute essays on special topics of current research interest. It is written at the level of the beginning graduate student in endocrinology, but should also serve as a useful reference for other scientists interested in endocrine systems and hormonal regulation of cellular function. Many clinicians and trainees should find this book a useful source of information on the relationship of molecular and cellular endocrinology to endocrine pathophysiology and therapeutic intervention.
This is a tremendous book, both in size and content.....The authors are to be congratulated on producing this long awaited authoritative text - TIBS; The book provides a current and much needed review of the rapidly changing field of endocrinology, advances in which have been spurred by advances in cellular and molecular biology - Besprechungs-Belege; Provides a wealth of useful information on the endocrine system in an affordable and reasonably portable form - Bioscience; Overall, I believe that this book should be welcomed as comprehensive and up to date textbook of endocrinology - FEBS Letters; the standard is fairly uniform and good, and the information mostly up-to-date. Particularly pleasing is the provision of relevant references on or near the page they service, and the plentiful supply of well-drawn diagrams and photomicrographs. It will serve a similarly useful purpose for basic scientists who need a handy reference book. The book is definately worth the money - Endocrine Journal
Hormones, a complex communications network - Etienne-Emile Baulieu; Commentary on neuroendocrinology - Roger Guillemin; The hypothalamus-pituitary system: an anatomical overview - Jean Racadot; Nerve cells and their chemical messages - Jacques Glowinski; From morphine to opioid peptides - Etienne-Emile Baulieu; Growth hormone and prolactin - Paul A. Kelly; Growth factors - Denis Gospodarowicz; Receptor-mediated endocytosis - Ira Pastan and Mark C. Willingham; ACTH and related peptides - Dorothy Krieger and Anthony Liotta; Hormones of the immune system - Jean Francois Bach; Glycoprotein hormones: gonadotropins and thyrotropin - Fernand Labrie; Contraceptive choices - Sheldon J. Segal; Vasopressin and oxytocin - Serge Jard; Melatonin: a neurohormonal mystery - Etienne-Emile Baulieu; The adrenal medulla - Jacques Hanoune; The adenylate cyclase system - Lutz Birnbaumer; Thyroid hormones - Serge Lissitzky; Gene structure and control of transcription - Pierre Chambon; Gene transcription and protein synthesis - Phillip A. Sharp; Steroid hormones - Edwin Milgrom; Hormonal control of the masculinization of the body - Alfred Jost; Clinical endocrinology of reproduction - Samuel S. C. Yen; Hormones and in vitro fertilization - Robert G. Edwards, Colin M. Howles and Michael C. Macnamee; Radioimmunoassay of peptide hormones - Rosalyn S. Yalow; Pancreatic hormones - Pierre Freychet; Lipoprotein receptors - Michael S. Brown and Joseph L. Goldstein; Gastrointestinal hormones - Bernard Desbuquois; Prostaglandins and related compounds - Elisabeth Granstrom, Par Westlund and Bengt Samuelsson; The renin-angiotensin aldosterone system and atrial natriuretic factor - Pierre Corvol and Joel Menard; Calmodulin - Anthony R. Means; Calcium regulatory hormones - Pierre Royer and Bryon Kemper; Chromosomal localization of genes of hormones, growth factors, receptors and other genes related to the endocrine system.
Number Of Pages: 700
Published: November 1990
Publisher: Chapman and Hall
Country of Publication: FR
Dimensions (cm): 27.94 x 20.96
Weight (kg): 1.57