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Histocompatibilty Testing : A Practical Approach - Philip Dyer

Histocompatibilty Testing

A Practical Approach

By: Philip Dyer (Editor), Derek Middleton (Editor)

Paperback Published: 3rd June 1993
ISBN: 9780199633630
Number Of Pages: 326

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Successful transplantation depends on the minimization of immunological differences between the donor and recipient tissues. These differences are based on polymorphisms of the human major hisotocompatibility complex which play a major role in determining the acceptance or rejection of allografts during transplantation. This book describes methods for the investigation of these polymorphisms at the gene and protein levels, and their application to the clinical transplantation of human organs and bone marrow. There is currently no other text available covering these up-to-date serological and molecular techniques in this area of immunogenetics, despite their importance to fundamental research, clinical practice and forensic medicine. This book will therefore be of interest to researchers in many subject areas, irrespective of whether they are in established laboratories or are entering this field for the first time.

'a very useful book and one might safely predict that it will become a standard text on the practical aspects of histocompatibility testing' J. Andrew Bradley, Western Infirmary, Glasgow, Immunology Today, Vol. 15, No. 6, 1994

W.F. Bodmer: Preface P.A. Dyer and D. Middleton: Introduction 1: D. Middleton, J.G. Bodmer, S. Marsh, and J.H. Heyes: Typing antisera 2: P.A. Dyer and C. Darke: Clinical HLA typing by cytotoxicity 3: S. Martin and F. Claas: Antibodies and crossmatching for transplantation 4: D. Savage, D. Middleton, L.A. Baxter-Lowe, and J. Gorski: Molecular methods 5: N.L. Reinsmoen: Cellular methods 6: P. Parham, and A.-M. Little: Gene and protein sequence polymorphisms 7: M. Rose: HLA antigens in tissues 8: E. du Toit: Paternity testing 9: D. Campell, J. Trowsdale, and I. Dunham: Non-HLA genes of the Mhc 10: P.A. Dyer, and D. Middleton: Data tables

ISBN: 9780199633630
ISBN-10: 0199633630
Series: Practical Approach Series
Audience: Professional
Format: Paperback
Language: English
Number Of Pages: 326
Published: 3rd June 1993
Publisher: Oxford University Press
Country of Publication: GB
Dimensions (cm): 1.1 x 1.1  x 1.1
Weight (kg): 0.56