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High Dilution Effects : Physical and Biochemical Basis - Nirmal C. Sukul

High Dilution Effects

Physical and Biochemical Basis

Hardcover

Published: 29th June 2004
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Since the subject of high dilution effects is still a subject for debate, this volume provides evidence in support of effects from control clinical studies, clinical records from veteran physicians, controlled experiments on animals and plants, and in vitro tests without any organisms (Chapter II). An overview of the methods for preparing drugs at ultra high dilution is also provided as well as the basic principles of homeopathy, which has been alleviating human suffering through the use of these drugs for several hundred years (Chapter I). Chapter III provides physical basis of high dilutions as evidence from the NMR, IR, UV and fluorescence spectra of those drugs. Since water is used as the diluents media, the structure and dynamics of water polymers in relation to high dilution are discussed in order to facilitate easy comprehension of this physical aspect, the basic principles of spectroscopy are also described. Chapter IV focuses on the mechanism of action of potentized drugs in the living system, discussing the structure of the cell, the plasma membrane, the integral proteins on the membrane, the interaction between these proteins and high dilutions and the manifestations of the therapeutic effects of high dilutions. Some aspects, peculiar to homeopathy, such as the chief miasm psora, and the literalities and time modalities of symptoms and drug action are interpreted from a scientific perspective. Chapter IV ends with a brief discussion on water structures and the origin of life to show the natural evolution of high dilution effects. The book not only helps in understanding the physical basis of high dilutions and their mechanism of action in organisms but provides many new avenues of investigation into this interdisciplinary field of science.

Prefacep. xi
Introductionp. 1
Preparation of high dilution of drugsp. 3
Sources of drugsp. 3
Plant materialsp. 3
Animal substancesp. 3
Minerals and chemicalsp. 4
Other biological materialsp. 4
Proving of drugsp. 4
Preparation of mother tincturesp. 5
Potentization of drugsp. 5
Succussionp. 5
Triturationp. 6
Conversion of solid potencies into liquid onesp. 7
Preservation of remedies and pharmaceutical formsp. 7
Summaryp. 8
Evidences for high dilution effectsp. 11
Clinical evidencesp. 11
Experimental evidences from animalsp. 14
Biological effects on mammals and birdsp. 15
Catalepsy modelp. 16
Oral route effectivep. 16
Dose responsep. 16
Righting reflex modelp. 17
Aqueous ethanol, the effective mediump. 17
Biological effects on amphibiansp. 17
Young toadsp. 17
Adult toadsp. 18
Effects on chronic alcoholismp. 18
Ethanol intakep. 18
Ethanol-induced neuropathyp. 20
Effects on parasitic diseasesp. 21
Electrophysiological studiesp. 23
Lateral hypothalamic neurons of catsp. 24
Medial frontal cortex neurons of an awake ratp. 25
Hypothalamic neuronal responses of alcoholic rats to Nux vomicap. 26
Hypothalamic neuronal responses of rats on salty diet to Natrum murp. 27
Effects on synaptic transmissionp. 28
Experimental evidences from plantsp. 31
Effect on parasites and pathogens of plantsp. 32
Evidences from in vitro testsp. 33
Boyd's in vitro experiment and other related experimentsp. 34
In vitro experiment on red blood cellsp. 36
Summaryp. 37
Physical basis of drugs at high dilutionsp. 39
NMR spectroscopyp. 40
NMR spectra of homeopathic potenciesp. 46
Infra-red spectroscopyp. 51
IR spectra of homeopathic potenciesp. 52
Fourier Transform spectroscopyp. 54
Electronic spectroscopyp. 55
Charge-transfer interactionp. 59
Solvation and electronic spectrap. 60
Electronic spectra of homeopathic potenciesp. 60
Spectrofluorometryp. 65
Application of fluorescence spectroscopy to homeopathyp. 66
Thermoluminiscencep. 68
Molecular association and water structurep. 68
Structure and dynamics of liquid waterp. 70
Transport phenomena in waterp. 72
Action of a homeopathic potencyp. 73
Water structure in presence of solutesp. 73
Trituration and nano particlesp. 75
Aqueous ethanol as a mediump. 76
Summaryp. 76
Mechanism of action of potentized drugsp. 79
Lateralities and Homeopathyp. 79
Time modalities and Homeopathyp. 80
Similia principle and Homeopahtyp. 81
Non-linear systems and Homeopathyp. 82
Miasms and their biological basisp. 84
Polycrests, reappearance of past diseases and holismp. 85
Action of drugs at ultra high dilutionsp. 86
Water as informational moleculesp. 86
Two components of a homeopathic potencyp. 87
Primary biomolecular target for a homeopathic potencyp. 88
The cell and the plasma membranep. 89
Membrane proteinsp. 90
Biomolecules in continuous water mediump. 91
Aquaporinsp. 92
Distribution in animalsp. 93
Water Pumpp. 93
Aquaporins in plantsp. 94
Aquaporins in fungi and bacteriap. 94
Structure of aquaporinp. 95
Function of aquaporin: passage of waterp. 96
Regulation of function of aquaporin and diseasep. 96
Interaction between a potency and biomoleculesp. 98
Role of carbohydrates in recognition processp. 101
Structured water and early lifep. 103
Summaryp. 104
Referencesp. 107
Subject Indexp. 121
Author Indexp. 127
Table of Contents provided by Rittenhouse. All Rights Reserved.

ISBN: 9781402021558
ISBN-10: 1402021550
Series: Handbooks of Behavioral Neurobiology
Audience: Tertiary; University or College
Format: Hardcover
Language: English
Number Of Pages: 130
Published: 29th June 2004
Publisher: Springer-Verlag New York Inc.
Country of Publication: US
Dimensions (cm): 23.2 x 15.6  x 1.27
Weight (kg): 0.84