Handbook of Mouse Mutations with Skin and Hair Abnormalities

PART I. BIOLOGY OF SKIN AND HAIR OF LABORATORY MICE AND HUMAN BEINGS -- Introduction -- Chapter 1. Applications and Needs of Models for Dermatological Research /Lowell A. Goldsmith -- Chapter 2. Inbred Laboratory Mice as AnimaJ Models and Biomedical Tools: General Concepts /John P. Sundberg -- Chapter 3. The Jackson Laboratory Mouse Mutant Resource /Muriel T. Davisson -- Chapter 4. Hair Follicle Stem Cells /Robert M. Lavker, Tung-Tien Sun, and John P. Sundberg -- Chapter 5. The Mouse Skin as a Model for Chemical Carcinogenesis /Claudio J. Conti -- Chapter 6. Viral Induced Skin Tumors in Mice /John P. Sundberg, Hendrick G. Bedigian, and Roderick Bronson -- Chapter 7. Hair Types and Subtypes in the Laboratory Mouse /John P. Sundberg and Margaret E. Hogan -- Chapter 8. Growth Factors and Cutaneous Pathology /Lloyd E. King, Jr., Lillian B. Nanney, and Ronald E. Gates -- Chapter 9. Transgenic Mice with Cytokine Mutations Affecting the Skin /Manfred Blessing, Erby Wilkinson, and Brigid L. M. Hogan -- Chapter 10. Epidermal Keratins /Joseph A. Rothnagel and Dennis R. Roop -- Chapter 1 1. Hair Follicle Keratins /George E. Rogers and Barry C. Powell -- Chapter 12. Keratinocyte Cultures as Models for DermatologicaJ Disease /Mark R. Pittelkow -- Chapter 13. Mouse Mutations with Endocrine Functional Consequences /Wesley G. Beamer -- Chapter 14. The Immune System in Cutaneous Disease: the Search for a Mouse Model of the Lmmunopathology of Psoriasis /Susan F. Grammer and J. Wayne Streilein -- PART II. ANIMAL MODELS OF GENETIC BASED SKIN DISEASES Section A. Mouse Single Gene Mutations -- Introduction -- Chapter 1. The Adrenocortical Dysplasia (acd) Mutation, Chromosome 8 /John P. Sundberg, Seth J. Orlow, Hope O. Sweet, and Wesley G. Beamer -- Chapter 2. The Angora (go) Mutation, Chromosome 5 /John P. Sundberg -- Chapter 3. The Asebia (ab, ab1) Mutations, Chromosome 19 /John P. Sundberg -- Chapter 4. The Atrichosis (at) Mutation, Chromosome 10 /John P. Sundberg -- Chapter 5. The Balding (bal) Mutation, Chromosome 18 /John P. Sundberg -- Chapter 6. The Bare-Patches (Bpa) Mutation, Chromosome X /John P. Sundberg -- Chapter 7. The Bareskin (Bsk) Mutation, Chromosome 11 /John P. Sundberg -- Chapter 8. The Beige (bg) Mutation, Chromosome 13 /John P. Sundberg -- Chapter 9. The Caracul (Ca and Cad) Mutations, Chromosome 15 /John P. Sundberg and Hope O. Sweet -- Chapter 10. The Chronic Proliferative Dermatitis (cpd) Mutation, Chromosome ?. Harm HogenEsch, Marion J. J. Gijbels, and Chris Zurcher -- Chapter 11. The Crinkled (cr) Mutation, Chromosome 13 /John P. Sundberg -- Chapter 12. The Curly-Whiskers (cw) Mutation, Chromosome 9 /John P. Sundberg -- Chapter 13. The Depilated (dep) Mutation, Chromosome 4 /John P. Sundberg and Seth J. Orlow -- Chapter 14. The Downless (dl) and Sleek (Dlslk) Mutations, Chromosome 10 /John P. Sundberg -- Chapter 15. The Ferrochelatase Deficiency (FechmlPas) Mutation, Chromosome 18 /Xavier Montagutelli -- Chapter 16. The Flaky Skin (fsn) Mutation, Chromosome? /John P. Sundberg, Dawnalyn Boggess, Leonard D. Shultz, and Wesley G. Beamer -- Chapter 17. The Flaky Tail (ft) Mutation, Chromosome 3 /John P. Sundberg -- Chapter 18. The Frizzy (fr) Mutation, Chromosome 7 /John P. Sundberg -- Chapter 19. The Fuzzy (fz) Mutation, Chromosome 1 /John P. Sundberg -- Chapter 20. The Greasy (Gs) Mutation, Chromosome X /John P. Sundberg -- Chapter 21. The Hair Interior Defect (hid) Mutation, Chromosome? /John P. Sundberg -- Chapter 22. The Hairless (hr) and Rhino (hrrh) Mutations, Chromosome 14 /John P. Sundberg -- Chapter 23. The Hair Patches (Hpt) Mutation, Chromosome 4 /John P. Sundberg -- Chapter 24. The Hairy Ears (Eh) Mutation, Chromosome 15 /John P. Sundberg and Seth J. Orlow -- Chapter 25. The Harlequin (Hq) Mutation, Chromosome X /John P. Sundberg -- Chapter 26. The Ichthyosis (ic) Mutation, Chromosome 1 /John P. Sundberg and Mark R. Pittelkow -- Chapter 27. The Lethal Milk (Im) Mutation, Chromosome 2 /John P. Sundberg and Hope O. Sweet -- Chapter 28. The Lustrous ( / /) Mutation, Chromosome 11 /John P. Sundberg -- Chapter 29. The Matted (ma) Mutation, Chromosome 3 /John P. Sundberg -- Chapter 30. The Motheaten (me) and Viable Motheaten (mev) Mutations, Chromosome 6 /Leonard D. Shultz and John P. Sundberg -- Chapter 31. The Mottled Locus: Mottled (Mo), Blotchy (Mobl°), Brindled (Mobr), Dappled (Modp), Mosaic (Moms), Tortoiseshell (Mow), and Viable Brindled (Movbr) Mutations, Chromosome X / -- John P. Sundberg -- Chapter 32. The Naked (N) Mutation, Chromosome 15 /John P. Sundberg -- Chapter 33. The Nude (nu) and Streaker (nustr) Mutations, Chromosome 11 /John P. Sundberg -- Chapter 34. The Ragged (Ra) and Opossum (Raop) Mutations, Chromosome 2 /John P. Sundberg -- Chapter 35. The Repeated Epilation (Er) Mutation, Chromosome 4 /Jean-Louis Guenet, Josselyne Salaun, and Berthe Salzgeber -- Chapter 36. The Rex (Re), Wavy Coat (Rewl), and Denuded (Reden) Mutations, Chromosome 11 /John P. Sundberg -- Chapter 37. The Satin (sa) Mutation, Chromosome 13 /John P. Sundberg -- Chapter 38. The Scurfy (sf) Mutation, Chromosome X /Virginia L. Godfrey -- Chapter 39. The Severe Combined Immunodeficiency (scid) Mutation, Chromosome 16 /John P. Sundberg and Leonard D. Shultz -- Chapter 40. The Shaven (Sha) Mutation, Chromosome 15 /John P. Sundberg -- Chapter 41. The Silver (si) Mutation, Chromosome 10 /Seth J. Orlow and John P. Sundberg -- Chapter 42. The Soft Coat (soc) Mutation, Chromosome 3 /John P. Sundberg -- Chapter 43. The Sparse-Coat (spc) Mutation, Chromosome 14 /John P. Sundberg -- Chapter 44. The Sparse-Fur (Otcspf) and Abnormal Skin and Hair (Otcash) Mutations, Chromosome X /John P. Sundberg and Donald P. Doolittle -- Chapter 45. The Tabby (Ta), Tabby-c (Tal), and Tabby-J (TaJ) Mutations, Chromosome X /John P. Sundberg -- Chapter 46. The Tight-Skin (Tsk) Mutation, Chromosome 2 /John P. Sundberg -- Chapter 47. The Vitiligo (mivu) Mutant Allele of the Microphthalmia Locus, Chromosome 6 /M. Lynn Lamoreux and Seth J. Orlow -- Chapter 48. The Wellhaarig (we, weMr) Mutations, Chromosome 2 /John P. Sundberg -- Section B. Purported Polygenic Mouse Skin Diseases -- Introduction -- Chapter 1. Chronic Ulcerative Dermatitis in Black Mice /John P. Sundberg, Kathy S. Brown, and William M. McMahon -- Chapter 2. Barbering Behavioral Abnormalities in Inbred Laboratory Mice /William M. McMahon and John P. Sundberg -- Chapter 3. Alopecia Areata in Aging C3H /HeJ Mice /John P. Sundberg, Colleen M. Vallee, and Lloyd E. King, Jr. -- Section C. Nonmurine Animal Models of Genetic Based Skin Diseases -- Chapter 1. Selected Heritable Skin Diseases of Domesticated Animals /Robert W. Dunstan and Robert A. Kennis -- Index.