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Glycoscience : Synthesis of Substrate Analogs and Mimetics - Hugues Driguez


Synthesis of Substrate Analogs and Mimetics

By: Hugues Driguez (Editor), Joachim Thiem (Editor)

Paperback Published: 1st April 1999
ISBN: 9783540655466
Number Of Pages: 321

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The synthesis of very complex saccharide structures is one of the most challenging areas of modern glycoscience. This volume presents the state of the art of complex carbohydrate synthesis, written by leading scientists whose groups are making major contributions in the field. Reflecting the particular interest in inhibitors and modulators as well as in mimetics, an in-cepth treatment is given both of their selective syntheses and of their biological implications. In addition the concept of multivalent glycoconjugate recognition as well as supramolecular implications of amphiphilic carbohydrates are highlighted.

Nucleophilic C-Glycosyl Donors for C-Glycoside Synthesisp. 1
Synthesis of C-Glycosides of Biological Interestp. 55
Thiooligosaccharides in Glycobiologyp. 85
Aldonolactones as Chiral Synthonsp. 117
Chemical and Chemo-enzymatic Approaches to Glycosidase Inhibitors with Basic Nitrogen in the Sugar Ringp. 157
The Synthesis of Novel Enzyme Inhibitors and Their Use in Defining the Active Sites of Glycan Hydrolasesp. 187
Heparinoid Mimeticsp. 215
Recent Developments in the Rational Design of Multivalent Glycoconjugatesp. 241
Amphiphilic Carbohydrates as a Tool for Molecular Recognition in Organized Systemsp. 275
Table of Contents provided by Blackwell. All Rights Reserved.

ISBN: 9783540655466
ISBN-10: 3540655468
Series: Springer Desktop Editions in Chemistry
Audience: General
Format: Paperback
Language: English
Number Of Pages: 321
Published: 1st April 1999
Publisher: Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
Country of Publication: DE
Dimensions (cm): 23.55 x 15.62  x 1.91
Weight (kg): 0.45

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