The subject of the book is global infectious diseases and includes 12 entities that were carefully selected for diversity of epidemiology, transmission, pathogenesis, and immune mechanisms. Each topic (schistosomiasis, malaria, filariasis, arboviruses, diarrheal diseases, AIDS, hepatitis, fungal diseases, Chagas' disease, rickettsial diseases, Lyme disease, and cysticercosis) is particularly interesting in its own right. Each entity will be reviewed by an expert who perceives the big picture and will cover the epidemiology, ecology, pathogenesis, immunity, and relevant molecular data pertinent to the etiologic agents and their hosts. Each expert will then express his opinion as to the best approach to eridicate, control, or contain the disease in the near future by attacking the most vulnerable point in the interaction of the etiologic agent and the host or the environment. Molecular approaches will be described which point towards novel methods to stimulate affective immunity, eradicate a vector, render it genetically incompetent, or develop a new therapeutic intervention.
The ultimate standard and the reasons for its success and the failure of other eradication campaigns will be posed by Dr. D.A. Henderson, leader of the successful campaign to eradicate smallpox and currently a high level advisor in the White House.
Infectious Diseases in Developing Countries: An Introduction to the Major Problems in Global Medicine.- The Challenge: Biotechnology Transfer to Public Health, Examples from Arbovirology.- AIDS: The Uses and Limitations of Science.- Strategies for Control of Viral Hepatitis in the Age of Molecular Biology.- Rickettsial Diseases: From Epidemiology to Molecular Biology. The Pathway Toward Disease Control.- Diarrheal Diseases: New Challenges and Emerging Opportunities.- Prospects for Control of Malaria in the Twenty-First Century.- Black Fungi: A Model for Understanding Tropical Mycoses.- Schistosomiasis: From Genes to Latrines.- Filariasis: Present Status and Future Challenges.- Current Issues in Cysticercosis: Proteins, Proglottids, Pigs, and Privies.- Antigenic Variation in Borrelial Diseases of Humans.- Perspectives on Chagas' Disease in Latin America and the United States.- Strategies for the Twenty-First Century - Control or Eradication?.